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Alzheimers

Fixing Rogue Brain Cells To Treat Neurodegenerative Diseases Like Alzheimer’s and Parkinson’s

A new study reveals a potential treatment strategy for neurodegenerative diseases by targeting astrocytes with drugs that inhibit HDAC3, protecting nerve cells and offering hope for advancements in therapies for conditions such as Alzheimer’s and Parkinson’s. Credit: SciTechDaily.com Researchers identify new therapeutic approach targeting astrocytes, the brain’s most abundant cells.A team led by scientists at the Case Western Reserve University School of Medicine has identified a new therapeutic approach for combating…

The Mysterious Case of The Youngest Person Ever Diagnosed With Alzheimer’s : ScienceAlert

In 2023, neurologists at a memory clinic in China diagnosed a 19-year-old with what they believed to be Alzheimer's disease, making him the youngest person ever to be diagnosed with the condition in the world.The male teenager began experiencing memory decline around age 17, and the cognitive losses only worsened over the years.Imaging of the patient's brain showed shrinkage in the hippocampus, which is involved in memory, and his cerebrospinal fluid hinted at common markers of this most common form of…

Scientists Unveil 145 Genes Vital for Genome Health

A groundbreaking study has unveiled key genes linked to DNA damage, offering new perspectives on cancer, neurodegenerative diseases, and potential therapies. This research underscores the significance of maintaining genome stability for health and disease management.Scientists unveil 145 genes vital for genome health, and possible strategies to curb progression of human genomic disorders.More than one hundred key genes linked to DNA damage have been uncovered through systematic screening of nearly 1,000 genetically…

How Tiny Polymers Are Outsmarting Neurodegenerative Diseases

Researchers have found a new way to boost the body’s defense against neurodegenerative diseases by preventing the degradation of Nrf2, potentially slowing the progression of diseases such as Alzheimer’s and Parkinson’s. Credit: SciTechDaily.comA groundbreaking study introduces a new method of targeting ‘undruggable’ proteins to fight neurodegenerative diseases by enhancing cellular antioxidant defenses, offering new hope for treatment advancements.Researchers led by Northwestern University and the University of…

The plan to diagnose Alzheimer’s in people with no memory problems

In a darkened Amsterdam conference hall this summer, a panel of industry and academic scientists took the stage to announce a plan to radically expand the definition of Alzheimer’s disease to include millions of people with no memory complaints.Those with normal cognition who test positive for elevated levels of certain proteins that have been tied to Alzheimer’s — but not proven to cause the disease — would be diagnosed as having Alzheimer’s Stage 1, the panel members explained. Even before the presentation ended,…

Alzheimer’s Linked to Epigenetic Changes in Immune Cells Outside The Brain : ScienceAlert

Immune cells in the blood of people with Alzheimer's disease exhibit subtle changes to how their genes are read, which could be a way the body primes itself to fight this insidious neurodegenerative disorder.Researchers from Northwestern University in the US found sections of DNA in the peripheral immune cells of Alzheimer's patients unwind in a specific way, exposing genes that could help mount a response inside the brain.While much research has focused on the immune system operating within or near the brain in patients…

Scientists Discover New Telltale Sign of Alzheimer’s

A groundbreaking study led by UCSF has provided comprehensive insights into posterior cortical atrophy (PCA), linking it strongly to Alzheimer’s disease with data from over 1,000 patients globally. This research highlights the unique challenges faced by PCA patients, including visuospatial difficulties, and stresses the importance of early detection and potential treatment options. The findings underscore the need for increased awareness and diagnostic precision to improve patient care and advance Alzheimer’s research.…

Scientists Discover Fascinating Link Between Regular Exercise and Better Brain Health

A recent study reveals that regular physical activity, even at moderate levels, is linked to increased brain volumes in areas important for memory and learning, offering a straightforward approach to enhancing brain health and reducing the risk of Alzheimer’s disease.An international study involving clinical researchers from the Pacific Neuroscience Institute’s Brain Health Center at Providence Saint John’s Health Center has uncovered a fascinating connection between regular exercise and improved brain health.The study’s…

Viagra and Similar Drugs Might Help Keep Alzheimer’s at Bay

One of the world’s most famous drug classes may have another trick up its sleeve. In a new study, scientists in the UK have found that erectile dysfunction drugs like sildenafil (more widely known as Viagra) are linked to a lowered risk of Alzheimer’s disease, the most common form of dementia. The findings don’t prove a cause-and-effect connection, the team says, but do merit clinical trials that could confirm a genuine benefit.'More People Need to Know About This History': A Black Astronaut Speaks About Race and…

Erectile Dysfunction Drugs May Lower Risk of Alzheimer’s : ScienceAlert

A new study of nearly 270,000 men suggests a pharmaceutical commonly used for erectile dysfunction sold commercially under brand names like Viagra may lower the risk of Alzheimer's disease by some 18 percent.But more research in the form of clinical trials is needed to understand optimal dosage, treatment time, and whether the slight protective effect extends to women."We desperately need treatments that can prevent or delay the development of Alzheimer's disease," says study author Ruth Brauer, a pharmacoepidemiologist…