Biomarkers

Research indicates that combining CRP and MHR levels in a blood test offers a more precise way to predict type 2 diabetes risk, with findings emphasizing chronic inflammation’s impact and the potential for early, personalized preventive measures.A new study by Edith Cowan University (ECU) suggests that a blood test may be able to evaluate a patient’s likelihood of developing type 2 diabetes.The most commonly used inflammatory biomarker currently used to predict the risk of type 2 diabetes is high-sensitivity C-reactive…

By University of Texas M. D. Anderson Cancer Center February 13, 2024A study from The University of Texas MD Anderson Cancer Center reveals that combining targeted therapy and immunotherapy, specifically durvalumab and ceralasertib, significantly benefits patients with non-small cell lung cancer (NSCLC).Phase II trial finds durvalumab plus ceralasertib boosted immune response and improved outcomes in patients with lung cancer.A specific combination of targeted therapy and immunotherapy may better help patients with…

The scientists found that people with long covid exhibit changes in a suite of proteins involved in the complement system, which helps the immune system destroy microbes and clear away cellular debris. The results echo what at least one other group has found.  None of the existing research proves that these changes drive the disease. But they offer up a new avenue for treatment exploration by helping doctors pick the best people to trial certain drugs “There aren’t really any effective therapies,” says Aran…

Researchers at UC San Diego School of Medicine have discovered a connection between depression and cellular metabolism, identifying specific blood markers that indicate a higher risk of suicide. Their study, published in Translational Psychiatry, suggests new methods for personalizing mental health care and potential new drug targets, focusing on metabolic deficiencies and mitochondrial dysfunction.University of California, San Diego study suggests new way to personalize mental health care.Major depressive disorder…

The biosensor and reader are designed to be used at home or at a point of care. The system can transmit results wirelessly to physicians, patients, and patient’s caregivers and family. Credit: David Baillot/University of California San DiegoThe next steps involve testing saliva and urine samples with the biosensor.An international team of scientists has created a handheld, non-invasive device that can detect biomarkers for Alzheimer’s and Parkinson’s Diseases. This biosensor can also wirelessly send the findings to a…

3D structures formed by human pancreatic cancer cells. WEHI researchers are working on developing the first diagnostic test for pancreatic cancer, that could help triple the survival rate of pancreatic cancer by 2030. Credit: WEHIPanKind’s funding supports vital research for a pioneering early-detection blood test for pancreatic cancer, potentially revolutionizing the diagnosis and treatment of this highly fatal disease in Australia.Research that could lead to the first early-detection blood test for pancreatic cancer has…

Researchers have used a machine-learning model to analyze blood proteins to estimate the biological, as opposed to the chronological, age of bodily organs. It’s a way of predicting an apparently healthy person’s risk of developing conditions like heart failure, Alzheimer’s disease, and diabetes that may lead to earlier treatment.Chronological age doesn’t always correspond with biological age. The aging process can cause a deterioration in the structure and function of organs that increases the risk of most chronic…

A new study of Alzheimer’s disease combines multiple biomarkers to uncover new genetic pathways and sex-specific differences, paving the way for improved early diagnosis and understanding of Alzheimer’s. Dementia, encompassing conditions like Alzheimer’s disease, impacts approximately 1.8 million individuals in Germany. The precise origins of this disease are still not fully understood, though it’s acknowledged that genetics are a major contributor to its development. Historically, most research efforts to discover new…

Because of the logistics and invasive procedures involved, many people put off getting tested for Alzheimer’s and Parkinson’s diseases. Thanks to a new portable device, however, such testing could soon be performed non-invasively at just about any location.Ordinarily, testing for neurodegenerative diseases such as Alzheimer’s and Parkinson’s requires patients to travel to a hospital or clinic where they undergo a spinal tap and MRI scan. Needless to say, not many people are enthusiastic about doing so, plus they may lack…

Researchers have identified three new prostate cancer biomarkers that improve the visibility of cancer cells used by pathologists to grade the disease’s severity. The novel technique could assist in determining which patients require urgent treatment and those who don’t, potentially improving treatment outcomes for millions of men.In 2020, more than 1.4 million men were diagnosed with prostate cancer, and an estimated 375,304 died. The survival rates for prostate cancer depend on several factors, including the stage and…