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Disney, Pepsi, Uber Set to Report During Lackluster Earnings Season

PepsiCo Inc., Uber Technologies Inc. and Walt Disney Co. are among the companies slated to report earnings in the coming week, during an earnings season marked by cooling demand and throttled profits.  Their results will shed light on the evolving state of the economy as companies in technology and other sectors face a streak of layoffs, businesses and consumers slow their spending, and as the Federal Reserve works to quell inflation by raising…

Drug Prices Increase 5.6% as Government Ramps Up Pressure to Lower Costs

Pharmaceutical companies raised list prices of 983 arthritis, cancer and other prescription drugs by an average of 5.6% at the start of this year—restrained increases as the industry faces a new federal law aimed at lowering medicine costs. Pfizer Inc., Novartis AG and Eli Lilly & Co. are among the companies that took the price increases through Jan. 31, according to 46brooklyn Research, a nonprofit drug-pricing analytics group. In recent…

Blockbuster Arthritis Drug Humira Faces Competition From First Lower-Price Copycat in U.S.

AbbVie Inc.’s ABBV 0.65% arthritis therapy Humira is set to face its first competition in the U.S. from a near-identical copycat, the end of the exclusive run of what was for years the country’s biggest-selling drug.After two decades of patent protection and more than $135 billion in U.S. sales, Humira will contend with the near-identical version from Amgen Inc. AMGN 0.17% starting Tuesday, Amgen said. Other Humira…

Pfizer Expects Drop in Revenue as Covid Vaccine Demand Wanes

Pfizer is projecting revenue this year of between $67 billion and $71 billion, falling from last year’s approximate $100 billion, a record high for the company, the New York-based drug company said Tuesday. Stripping out Covid-19 products, Pfizer expects its 2023 revenue to grow 7% to 9%. “As we turn to 2023, we expect to once again set records, with potentially the largest number of new product and indication launches that we’ve ever had in such a short period of time,” Chief Executive Albert Bourla…

U.S. Appeals Court Sides With Drugmakers on Discount Program

A U.S. appeals court ruled that pharmaceutical companies can limit their shipments of federally-discounted drugs to pharmacies, in a major win for the drugmakers and a blow to hospitals and clinics that receive the low-priced medicines. The ruling on Monday, by a three-judge panel of the Philadelphia-based Third Circuit Court of Appeals, was in favor of drugmakers Sanofi SA, SNY 0.33% AstraZeneca AZN 0.33%…

Johnson & Johnson Fourth-Quarter Earnings Down 25%

Johnson & Johnson reported a 25% drop in earnings and declining sales for the fourth quarter as demand dropped for its Covid-19 vaccine, while providing a cautious forecast for sales growth as the company undergoes a big transformation.The New Brunswick, N.J., healthcare-products company said Tuesday that quarterly revenue fell 4.4% to $23.71 billion on fewer vaccine sales and a stronger dollar, below analyst estimates of $23.9 billion, according to FactSet. Earnings came in at $1.33 a…

Moderna’s RSV Vaccine Reduces Risk of Respiratory Diseases, Study Finds

An experimental vaccine from Moderna Inc. significantly reduced the risk of a viral respiratory disease among older adults in a large clinical trial, the latest promising sign in drugmakers’ efforts to fight the deadly RSV virus.Based on the results, the Cambridge, Mass., company said Tuesday it would apply in the coming months for U.S. regulatory approval to sell its vaccine against RSV, which stands for respiratory syncytial virus. If regulators approve, it could become available by early…

FDA Commissioner Denies Wrongdoing in Approval Process for Biogen Alzheimer’s Drug Aduhelm

U.S. Food and Drug Administration Commissioner Robert Califf defended his agency’s decision to approve the Alzheimer’s drug Aduhelm, after an investigation by House Democrats found close cooperation between the drug’s sponsor and regulators. Findings released late last year from the then-Democratic-led Oversight and Reform Committee and the Energy and Commerce Committee faulted the FDA for holding an unusual number of meetings with Biogen Inc. while it weighed…