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Alzheimer’s Might Not Actually Be a Brain Disease, Expert Reveals : ScienceAlert

The pursuit of a cure for Alzheimer's disease is becoming an increasingly competitive and contentious quest with recent years witnessing several important controversies.In July 2022, Science magazine reported that a key 2006 research paper, published in the prestigious journal Nature, which identified a subtype of brain protein called beta-amyloid as the cause of Alzheimer's, may have been based on fabricated data.One year earlier, in June 2021, the US Food and Drug Administration had approved aducanumab, an…

Berkeley Scientists Unveil Promising New Breakthrough

An illustration of a brain cell in a person with Alzheimer’s disease, showing the accumulation and clumping of tau proteins (blue squiggles) in the cytoplasm of a brain cell. Protein clumps, also known as aggregates, are thought to lead to cell death and dementia. New research suggests that such clumps may not cause brain cell death directly, but rather throw the cell’s response to stress off balance so that it never gets switched off. Credit: National Institute on Aging, National Institutes of HealthResearch from UC…

A First-of-Its-Kind Signal Was Detected in The Human Brain : ScienceAlert

Scientists have identified a unique form of cell messaging occurring in the human brain, revealing just how much we still have to learn about its mysterious inner workings.Excitingly, the discovery hints that our brains might be even more powerful units of computation than we realized.Back in 2020, researchers from institutes in Germany and Greece reported a mechanism in the brain's outer cortical cells that produces a novel 'graded' signal all on its own, one that could provide individual neurons with another way to…

New Research Challenges Long-Held Views on Brain Processing

Recent research reveals that body movements, specifically whisking in mice, modulate sensory processing in the brain differently than previously thought, challenging the established role of motor cortices. This discovery, which highlights the significant impact of secondary sensory and thalamus inputs, could revolutionize the development of technologies mimicking human sensory-motor integration.Scientists have revealed a new understanding of the impact of physical movements on sensory experiences, questioning traditional…

The Revolutionary Role of Delta Opioid Receptors

A study from the Tokyo University of Science shows that targeting delta opioid receptors (DOP) in the brain’s PL-BLA pathway with the agonist KNT-127 can significantly reduce anxiety-like behavior in mice, paving the way for new anxiety disorder treatments. Credit: SciTechDaily.comStudy reveals mechanistic roles of delta opioid receptors and specific neuronal pathways that are involved in anxiety-like behaviors in mice.Anxiety-related disorders can have a profound impact on the mental health and quality of life of…

Unlocking the Secrets to Early Alzheimer’s Detection

Advances in Alzheimer’s research have introduced groundbreaking diagnostic methods and treatments aimed at slowing disease progression. Early detection through biomarkers and blood tests offers a new horizon for effective intervention and personalized care strategies.Groundbreaking progress in Alzheimer’s treatment and diagnostics, including biomarkers and blood tests, heralds a new era of early intervention and personalized care in dementia research.Until recently, a diagnosis of dementia might help explain cognitive…

Underlying Cause of Long COVID “Brain Fog” Discovered

Researchers have made a groundbreaking discovery about Long COVID’s neurological effects, including brain fog and cognitive decline. By identifying blood vessel disruption in the brain, they offer new insights for diagnosing and treating the condition, potentially transforming the approach to post-viral neurological syndromes. Credit: SciTechDaily.comScientists uncover crucial links between Long COVID and brain blood vessel integrity, offering hope for new treatments and diagnostic methods.A team of scientists from…

How Does the Brain Make Decisions? Harvard Scientists Shed New Light

Scientists have discovered how neuron connections in the brain contribute to decision-making, revealed through a study involving mice navigating a maze. This research, led by neuroscientists at Harvard Medical School, marks the first to integrate structural, functional, and behavioral analysis to understand the neural underpinnings of choices. Credit: SciTechDaily.comA study on mice offers insights into how neurons communicate during the decision-making process.Researchers have uncovered new insights into the way brain…

What Ever Happened to Mad Cow Disease?

One of the most existentially frightening illnesses ever to be discovered was mad cow disease, a fatal prion-spread illness that appeared in animals in the 1980s and killed over 200 people during the height of the outbreak in the late 1990s. You don’t hear much about mad cow today, but the threat still looms. Here’s what happened to this nightmare germ.Dave Bautista Opens Up About His Relationship With Denis VilleneuveIn 1986, farmers in the UK began to report strange behavior among some of their cows. The affected…

Tiny Doses of LSD Boost Unique Signals in The Human Brain : ScienceAlert

Even small doses of LSD could have therapeutic benefits for mental health and task performance, a new study shows.Researchers from the US and Germany gave 21 adults either a placebo or 13 or 26 micrograms of LSD – small doses that rarely lead to hallucinatory effects.It was found that 26 micrograms of the psychoactive compound increased brain complexity by about 12 percent compared to a placebo, without altering consciousness. Neural complexity is a measure of unique brain signals, usually correlating with consciousness…