CellBased

For the first time, the FDA has approved two cell-based gene therapies for treating the rare but potentially fatal sickle cell disease. One is also the first approved therapy to utilize the CRISPR/Cas9 gene editing technology, signifying innovative advancement in the fields of gene therapy and regenerative medicine.Sickle cell disease (SCD) is a group of inherited blood disorders that affect hemoglobin, the oxygen-carrying protein in red blood cells. In someone with SCD, the hemoglobin is mutated, causing the red blood…

BharatBenz and Reliance First hydrogen fuel cell bus (File photo) Tata Motors and Ashok Leyland are also not so behind in the race. They are also putting efforts on the path of hydrogen-powered commercial vehiclesA commercial vehicle manufacturer in India BharatBenz has been working hard on its first intercity bus concept, powered by hydrogen fuel cell technology, for quite a long time. Now, the company in partnership with Reliance unveiled the heavy luxury commercial vehicle based on the technology at the 4th Energy…

Scientists have developed a universal receptor system for T cells that could lead to highly customizable CAR T cell and other immunotherapies for treating cancer and various diseases. The new approach involves engineering T cells with receptors containing a universal “SNAPtag” that can fuse with antibodies targeting different proteins. This allows treatments to be tailored for optimal immune responses. The researchers demonstrated the potential of their SNAP approach in CAR and SynNotch receptors, opening up possibilities…