Chemical Biology

A groundbreaking discovery of side openings in BK ion channels by researchers offers a new pathway for developing selective drugs to target these channels, addressing a significant challenge in ion channel drug development. Ion channels are crucial in health and disease, making them significant targets for drug development. However, selectively targeting specific ion channels remains a major challenge. Researchers at Weill Cornell Medicine and RMIT University in Australia have discovered unique side openings in BK…

Researchers have created a novel fluorogenic probe to illuminate the interactions between sugars and proteins, crucial for understanding various biological processes and diseases.Researchers at the University of Montreal’s Chemistry Department have created an innovative fluorogenic probe for analyzing interactions between sugars and proteins, two families of biomolecules essential to life.The findings by professor Samy Cecioni and his students, which open the door to a wide range of applications, were recently published…