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Model Organs Built With Cells From Living Fetuses : ScienceAlert

Scientists have grown small but complex models of human organs from live fetus cells for the first time, giving experts new insight into our development and potential treatments for malformations while in the womb.These organoids aren't full replicas of organs, but they're close enough to the real deal that they can be used to study disease and other aspects of human biology that are difficult to investigate in living people.In a new study carried out by an international team of researchers, lung, kidney, and intestine…

Organoids made from amniotic fluid will tell us how fetuses develop

Researchers have known for decades that amniotic fluid holds fetal cells. That’s what allows doctors to diagnose conditions like Down syndrome and sickle-cell disease before birth via amniocentesis, in which a needle is used to take a sample of the fluid. The vast majority of these cells, 95% or more, are dead cells sloughed off by the fetus, says Mattia Gerli, a stem cell biologist at University College London and an author of a paper on the work published in Nature Medicine today. But what the researchers homed in on…