Gladstone Institutes

A study reveals that people with long COVID have dysfunctional immune cells, showing chronic inflammation and abnormal movement into organs. Analyzing immune cells and molecules in 43 individuals, the research highlights a low-level viral persistence in long COVID, with a particular focus on T cells’ mismatched activity, paving the way for understanding and treating the condition.Researchers at Gladstone Institutes and the University of California, San Francisco, conducted analyses on immune cells from individuals with…

Gladstone Institutes researchers found that the Christchurch mutation in the APOE gene protects against the effects of APOE4, the primary risk factor for Alzheimer’s. This discovery, showing reduced neurodegeneration in Alzheimer’s models, opens up new possibilities for treatment and was published in Nature Neuroscience.New research sheds light on protective mechanisms of the “Christchurch mutation.”Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the “Christchurch mutation” can…