Groundbreaking gene therapy trial allows 5 children born deaf to hear
A breakthrough clinical trial using gene therapy has restored hearing to five children born deaf. After six months, the children were able to recognize speech and hold conversations, raising hopes for wider use in the near future.The patients in the trial suffered from a genetic condition called autosomal recessive deafness 9 (DFNB9), which is caused by a mutation in a gene called OTOF. This gene produces the otoferlin protein, which helps transmit electrical pulses from the cochlea to the brain, where it can be…