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Inhibitors

JAK Inhibitors Prove Highly Effective in Japanese Study

A new study has confirmed the effectiveness of JAK inhibitors in treating rheumatoid arthritis. The Japanese multicenter, retrospective study found high remission and low disease activity rates among patients, with the majority continuing treatment. This success highlights the potential of JAK inhibitors as a favorable alternative to conventional treatments, which often lead to reduced effectiveness and discomfort over time.A new study published in the journal Rheumatology reveals that JAK inhibitors, commonly used to…

How HDAC Inhibitors Tackle Pancreatic Cancer’s Fibrotic Wall

Researchers at the Salk Institute found that HDAC inhibitors are effective in treating pancreatic cancer by targeting fibroblasts, the cells responsible for the dense scar tissue around tumors. This approach both slows tumor growth and reduces fibroblast activation, offering a new strategy in combating this hard-to-treat cancer. Credit: SciTechDaily.com Salk researchers discovered that an anti-cancer therapy can prevent the activation of fibroblasts, cells that typically form protective barriers around pancreatic tumors.…