New Research Shines Light on Cause of Chronic Kidney Disease
Research has revealed that the Indian Hedgehog (IHH) protein, produced by specific cells in aged and damaged kidneys, drives scarring in kidneys and hearts, leading to chronic kidney disease (CKD). By blocking IHH or its activating protein TNF, fibrosis in kidney and heart tissues in mice models was reduced, offering potential new treatment pathways for CKD.A new understanding of a protein linked to kidney and heart damage might pave the way for novel treatment strategies for chronic kidney disease, according to recent…