Existing Drug That Kills Off Sleeping Bone Cells Could Provide Relief
Recent research suggests that Navitoclax, a drug targeting dormant cells, could be effective in treating lower back pain by focusing on senescent osteoclasts. These cells are essential for bone remodeling but can cause issues when they become senescent. The study demonstrates that Navitoclax significantly reduces senescent osteoclasts, leading to less spinal pain and degeneration in mice. The findings indicate a potential new strategy for lower back pain treatment, although further clinical trials are necessary for…