mechanisms

Hair follicle stem cells (green) mobilize and expand (white) to help repair the skin’s barrier by differentiating into epidermal lineages (red). Credit: Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development at The Rockefeller UniversityWhen a child falls off her bike and scrapes her knee, skin stem cells rush to the rescue, growing new epidermis to cover the wound. However, only a portion of these stem cells, which eventually repair the damage, are typically assigned the task of replenishing the…

Karolinska Institutet’s groundbreaking research using DNA origami reveals a novel way of activating the Notch cell receptor with a protein, Jag1, providing new insights into serious diseases and developmental processes. Credit: SciTechDaily.comResearchers at Karolinska Institutet in Sweden have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way. The result opens new avenues for understanding how the Notch signaling pathway…

Researchers at Kyoto University have made significant strides in understanding Down syndrome, focusing on the protein kinase DYRK1A. Their discoveries offer new insights into the molecular mechanisms of Down syndrome and autism spectrum disorder, as well as potential clinical applications for managing these conditions.A recent study uncovers the role of FAM53C in regulating DYRK1A, offering new insights into the cellular mechanisms of Down syndrome and potential clinical implications.Down syndrome, a congenital disorder…

Three-dimensional distribution, transport process and source attribution of ozone under extreme pollution events over Hefei. Credit: HU Feng Recently, a research group led by Prof. Xie Pinhua from Hefei lnstitutes of Physical Science (HFIPS), Chinese Academy of Sciences (CAS), revealed the source and transport mechanisms behind an episode of ozone pollution observed in Hefei, a city located in the Yangtze River Delta (YRD)…

Cancers can alter liver function, causing inflammation and fat buildup, according to a study from Weill Cornell Medicine. This finding opens possibilities for new tests and treatments for detecting and reversing this process.A study from Weill Cornell Medicine has shed light on a survival mechanism employed by cancers, which often emit molecules into the bloodstream that cause detrimental changes to the liver. These modifications shift the liver into a state of inflammation, leading to a buildup of fat and hindering its…

A parvalbumin interneuron (blue) surrounded by the perineuronal net. Credit: The Hospital for Sick Children (SickKids)How do our brains develop the ability to form particular memories? A pioneering preclinical study conducted by a research group at The Hospital for Sick Children (SickKids) might have discovered a molecular cause behind memory changes during early childhood.The type of memories often associated with the term “memory” are event-based memories, or episodic memories, which are associated with a certain…

Depression is a complex mental health disorder characterized by persistent feelings of sadness, hopelessness, and a lack of interest or pleasure in activities. Studies estimate that approximately 264 million people of all ages experience depression, making it one of the most prevalent mental illnesses globally.Clinical depression is a common psychiatric condition with often devastating consequences. A new study in Biological Psychiatry, published by Elsevier, enhances our fundamental understanding of the brain’s neural…

by KeAi Communications Co. Credit: CC0 Public Domain Digital platforms are powerful catalysts of economic activity, drastically reducing transaction and communication costs. This has sparked an abundance of scholarly research to explore the revolutionary changes they have caused in a variety of industries. It has similarly encouraged "platformania," which essentially entails speedy investment…

Schematic showing the expected future (2081-2100) warming pattern and the corresponding changes in winds and ocean heat transport for an SSP5-8.5 greenhouse gas emission scenario. Credit: Sahil Sharma A study published in Nature Communications by an international team of climate scientists uncovers the physical mechanisms that can cause uneven future warming in the Indian Ocean and corresponding shifts in monsoon…

- Consensus is a fancy word for agreement - Not every consensus mechanism serves the same function - Consensus is the key element that creates trust in a system.Read All - Consensus is a fancy word for agreement - Not every consensus mechanism serves the same function - Consensus is the key element that creates trust in a system.Read All FOLLOW US ON GOOGLE NEWS Read original article here Denial of responsibility! Techno Blender is an automatic aggregator of the all world’s media. In each content, the…