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The Link Between Inflammation And Chronic Back Pain May Not Be What We Thought

Inflammation is a core component of pain. But early inflammatory responses may protect against acute pain becoming chronic, according to an intriguing study of nearly 100 patients with low back pain.  At first glance, the study, which also included mouse models of persistent pain and a population-level analysis of painkiller use, seemingly goes against mounds of evidence indicating that inflammation drives widespread chronic pain.But its focus is on acute inflammation – the first wave of immune cells led by neutrophils,…

Gene That Shapes Mutation Rate Discovered in Mice

Scientists have located an area in the mouse genome where genetic variation is associated with differences in the mutation rate between individuals.The finding supports theory that genetic differences between individuals and species can affect the acquisition of mutations.Every organism is born with a few mutations in its genome that differ genetically from both of its parents. Such changes in an individual’s genetic code create the diversity that allows nature to select advantageous traits that drive the evolution of a…

Regular Weed Smoking Seems to Increase Cardiovascular Disease Risk, Study Shows

People who smoke cannabis more than once a month have an increased risk of heart disease and heart attack, a new study has found – but the same study has also identified a mechanism and a molecule that may counteract the risk.  While links between weed and poor heart health have already been identified, the latest research sheds more light on the mechanisms behind the relationship, as well as analyzing data from a huge sample: half a million individuals.In further tests on mice, the study also found that…

Fecal transplants reverse signs of aging in brain, gut and eyes of mice

The connection between gut bacteria and human health continues to be illuminated in all kinds of ways, and among the more fascinating is the way these microbes might influence different aspects of the aging process. A study has not only highlighted new facets of this relationship, but demonstrated how hallmarks of aging in the brain, gut and eyes might even be reversed through fecal transplants. The makeup of the microbial communities in our gut is being shown to shape many different aspects of our wellbeing, and we're…

Protein derived from corn boosts memory in mice with Alzheimer’s

Among the many ways scientists hope to be able to tackle Alzheimer's is by preventing it from taking hold in the first place, or at least averting its worst effects. This idea of a vaccine for Alzheimer's is gaining traction as scientists continue to devise new ways of clearing the brain of toxic proteins hypothesized to be key drivers of the condition. A newly published study has hinted at further possibilities in this area, with a protein derived from corn used to induce an immune response and improve memory in mice…

Exercise found to promote new blood vessel growth in diabetic mice

One of the harmful effects of diabetes is the way it impacts on the blood vessels, not only narrowing them to drive up the risk of stroke and heart attacks but preventing the formation of entirely new ones. Researchers have produced what they say is the first evidence that exercise can counter this consequence of the disease, and point to drugs already under development that could mimic these effects for sufferers of the disease.Exercise is a well-established way to manage diabetes, but there is still a lot for us to…

7 best mice of 2022: Top options that will click with any user

Computers are with us at the office, at home, at school, and in just about every other space we humans inhabit. As they continue to become a more and more prevalent part of our lives, the ways in which we interface with them grow more important as well. For the most casual users out there, any mouse or touchpad will likely do. But, if you're tech savvy enough to have clicked on this article, chances are you want a little bit more from…

The best wireless mice for 2022

It has been over 40 years since the first computer mouse shipped, and since then, we’ve learned to cut the cables. Wireless mice are a dime a dozen and are much more common now, but only a select few make our list of the best. It doesn’t matter if you’re shopping on a budget, focused on gaming, or have ergonomic needs — there’s a wireless mouse for you. We’ve rounded up the top wireless mice available in 2022, from a large trackball mouse like the Kensington Expert to an inexpensive portable powerhouse like the…

SteelSeries Aerox 9 Wireless, Aerox 5 Gaming Mice Launched

SteelSeries Aerox 9 Wireless and Aerox 5 gaming mice have been launched in the US. While the Aerox 9 is a fully wireless mouse, the Aerox 5 comes in both wireless and wired variants. With its new Aerox 5 wired mouse device, SteelSeries says it has produced the lightest 66g “multi-genre” mouse on the market. The Aerox 9 Wireless mouse features 18 programmable buttons and the company's TrueMove Air sensor. Similar to other existing Aerox mice, the new Aerox 9 and Aerox 5 are also IP54-certified against water and dust. It is…