microscopy

New research utilizing advanced imaging to track one million neurons in mice uncovers that over 90% of brain activity, previously considered noise, contains significant signals, revealing the mammalian brain’s underestimated complexity. Credit: SciTechDaily.comThe mammalian brain is a web of densely interconnected neurons, yet one of the mysteries in neuroscience is how tools that capture relatively few components of brain activity have allowed scientists to predict behavior in mice. It is hard to believe that much of the…

Scatter pattern produced by doughnut-shaped beams of light bouncing off of an object with a regularly repeating structure. Credit: Wang, et al., 2023, “Optica”To study nanoscale patterns in tiny electronic or photonic components, a new method based on lensless imaging allows for near-perfect high-resolution microscopy. Ptychography, a powerful form of lensless imaging, uses a scanning beam to collect scattered light for image reconstruction, facing challenges with periodic samples.To study nanoscale patterns in tiny…

Researchers at the University of Illinois Urbana-Champaign have introduced an AI technique that significantly improves Atomic Force Microscopy (AFM) by enabling it to visualize material features smaller than the probe’s tip. This breakthrough, offering the first true three-dimensional profiles beyond conventional resolution limits, promises to revolutionize nanoelectronics development and material studies.Atomic force microscopy, or AFM, is a widely used technique that can quantitatively map material surfaces in three…

Scientists from Trinity College Dublin and the Royal College of Surgeons in Ireland have developed innovative fluorescent dyes that change color to visualize different biological environments using a single dye. These dyes, capable of “switching on” and “off” based on their location within cellular structures, enable real-time, high-contrast imaging of cellular processes. This breakthrough, published in the journal Chem, paves the way for advancements in bio-sensing, drug delivery imaging, and the study of cellular…

A new study reveals that extended ketamine use leads to significant changes in the brain’s dopamine system, suggesting the need for targeted therapies. This groundbreaking research offers new insights into developing effective treatments for depression and eating disorders, emphasizing the importance of minimizing side effects and recreational abuse. Credit: SciTechDaily.comKetamine, once primarily known as an anesthetic and a recreational drug, has gained a new reputation due to its potential therapeutic benefits. This…

Schematic representation of the experimental setup: Attosecond pulses (violet) eject electrons (green) from a crystal surface. The photoemission electron microscope (cone-shaped instrument at top) examines the rapid movements of the electrons. Credit: Jan Vogelsang, editedA groundbreaking study by a Swedish-German team has tracked ultrafast electron dynamics with unparalleled precision, opening new avenues in nanomaterial and solar cell research.When electrons move within a molecule or semiconductor, this occurs on…

PicoRuler: Protein-based molecular rulers make it possible to test the optical resolution of the latest super-resolution microscopy methods on biomolecules in the sub-10-nanometer range under realistic conditions. Credit: Gerti Beliu, DALL-E 3 / University of Würzburg Good news for researchers working with high-resolution fluorescence microscopy: Biocompatible molecular rulers are available for the first time to calibrate the latest super-resolution microscopy methods. Recent advancements in super-resolution microscopy…

TU Wien researchers have revolutionized the understanding of catalyst promoters by directly observing the role of lanthanum atoms in enhancing rhodium nanoparticle catalysts. Their study reveals how these promoters control crucial areas of the catalyst, significantly impacting the chemical reaction process. Above is an image depicting water molecules and the nanoparticle. Credit: TU WienResearchers at TU Wien have made a significant breakthrough by observing the function of promoters in catalytic reactions in real-time…

Researchers at have developed a groundbreaking autofluorescent compound by combining artemisinin and coumarin, two plant-derived substances. This innovation allows for precise imaging in live cells and has proven effective against drug-resistant malaria pathogens, particularly plasmodium falciparum. The development of these autofluorescent hybrids, which can be observed without altering their effectiveness, represents a significant step forward in combating drug-resistant malaria.A research team at FAU has developed drugs…

Coronaviruses (round particles) with spike proteins (cyan) infect a host cell carrying sporadic ACE-2 receptors (pink). After membranes fuse and release viral components (purple). (violet) are released. Credit: RVZ WürzburgA new study reveals that the <span class="glossaryLink" aria-describedby="tt" data-cmtooltip="<div class=glossaryItemTitle>SARS-CoV-2</div><div class=glossaryItemBody>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the official name of the…