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Painkiller or pleasure? First conclusive evidence found for intentional use of black henbane in the Roman world

A) The bone cylinder and plug (reproduced from Groot & van Haasteren, 2017: fig. 14.14B); B) black henbane seeds (photograph by BIAX Consult). Credit: Antiquity (2024). DOI: 10.15184/aqy.2024.5 A team of archaeologists led by Dr. Maaike Groot from Freie Universität Berlin has provided the first firm evidence that the Romans deliberately collected and used the poisonous seeds of the black henbane plant.…

Vertex non-opioid painkiller shows positive late-stage trial results

A sign hangs in front of the world headquarters of Vertex Pharmaceuticals in Boston on Oct. 23, 2019.Brian Snyder | ReutersVertex Pharmaceuticals on Tuesday said its experimental painkiller, which is being tested as an alternative to addictive opioids, significantly decreased post-surgery pain in late-stage trialsThe drug, known as VX-548, did not work better than a popular opioid, however.Still, the trial results bring the biotech company one step closer to developing a drug that can provide strong pain relief without…

Vertex nonopioid painkiller posts positive midstage trial results

A sign hangs in front of the world headquarters of Vertex Pharmaceuticals in Boston on Oct. 23, 2019.Brian Snyder | ReutersShares of Vertex Pharmaceuticals jumped Wednesday after the company's painkiller, which is being tested as an alternative to opioids, significantly decreased pain in a midstage trial.Those positive results for diabetes patients suffering from a chronic nerve condition support the biotech company's hopes to develop a drug that can provide strong pain relief without the addictive potential of opioids.…

Painkiller Limited Series: Release Date, Trailer, Plot, and Where to Watch | Hollywood

Netflix just announced a limited series named Painkiller, which would focus on America's real-life opioid issue. This drama, starring Matthew Broderick and Uzo Aduba as the key characters, will follow a fictitious version of events that led to one of America's worst crises in recent years. The upcoming limited series Painkiller puts a sharp focus on the origins and aftermath of America’s opioid epidemic. Here's everything you need to know! The streaming platform released a trailer for the upcoming series,…

Painkiller producers could pivot to paper waste instead of crude oil

Paracetamol and ibuprofen are among the world’s most common over-the-counter painkillers, but manufacturing them requires crude oil. Now, researchers at the University of Bath have developed a more sustainable method, creating the drugs out of waste products from the paper industry.When we feel a headache coming on, many of us will just pop a pill without really thinking about where it came from. But many common pharmaceuticals, such as paracetamol/acetaminophen (the active ingredient in Tylenol and Panadol) and ibuprofen…

Researchers Point to the Source of Serious Side Effects in Widely-Used Painkiller

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to treat pain, inflammation, and fever. It works by blocking the production of prostaglandins, which are substances in the body that cause pain and inflammation. While diclofenac is effective in relieving pain and reducing inflammation, it can also cause side effects. It is important to talk to your doctor about the risks and benefits of taking diclofenac before starting treatment.According to recent research, the safety issues surrounding the…

Nerve-Cooling Implant Could Provide Pain Relief on Demand, Eliminate Need for Addictive Painkillers

Researchers have developers a flexible implant capable of relieving pain in patients. In what could be termed as a game-changing discovery, the implant is a water-soluble and biocompatible device that can serve as an alternative to painkillers — eliminating the need for addictive medications. By wrapping around the nerves to provide cooling in the region, the implant can numb the nerve and block pain signals to the brain, bringing relief from pain. Users can activate the implant via an external pump, while controlling the…