Plaques

Plastics are now everywhere, with tiny fragments found in several major organs of the human body, including the placenta.Given how easily the microscopic particles infiltrate our tissues, it's vital that we learn exactly what kinds of risks they could pose to our health.Researchers have been busy studying the effects of microplastics in mini-replicas of organs, and in mice, to get a sense of how they might impact the human body. However, the concentrations of microplastics used in those studies might not reflect people's…

Replica of the Valencina Slate Plaque with inserted owl feathers on the two drilled holes at the top of the plaque. Credit: Juan J. Negro Ancient owl-shaped slate engraved plaques, dating from about 5,000 years ago in the Iberian Peninsula, may have been created by children as toys, suggests a paper published in Scientific Reports. These findings may provide insights into how children used artifacts in ancient European…

Scientists found that green tea catechins and resveratrol, found in red wine and other foods, reduced the formation of plaques in Alzheimer’s-afflicted neural cells in the lab.Using a 3D neural tissue model, scientists found the compounds diminish amyloid plaques with no side effects.In the United States, <span class="glossaryLink" aria-describedby="tt" data-cmtooltip="<div class=glossaryItemTitle>Alzheimer’s</div><div class=glossaryItemBody>Alzheimer's disease is a…

The prevailing theory is that Alzheimer’s disease is caused by the buildup of amyloid plaques in the brain. However, new research finds that it is actually caused by a decline in levels of a specific protein.New research on patients with mutations published in the Journal of <span class="glossaryLink" aria-describedby="tt" data-cmtooltip="<div class=glossaryItemTitle>Alzheimer’s</div><div class=glossaryItemBody>Alzheimer's disease is a disease that attacks the brain,…

Rapamycin is also known as sirolimus and is sold under the brand name Rapamune.An innovative strategy to lessen the plaques was also found in the study.The oral administration of rapamycin to an <span class="glossaryLink" aria-describedby="tt" data-cmtooltip="<div class=glossaryItemTitle>Alzheimer’s</div><div class=glossaryItemBody>Alzheimer's disease is a disease that attacks the brain, causing a decline in mental ability that worsens over time. It is the most common…

Alzheimer's disease has long thwarted our best efforts to pinpoint its underlying causes. Now, a new study in mice suggests that 'poisonous flowers' bulging with cellular debris could be the root source of one hallmark of the wretched disease and a beautifully sinister sign of a failing waste disposal system inside damaged brain cells.  The study, led by neuroscientist Ju-Hyun Lee of New York University (NYU) Langone, challenges the long-standing idea that the build-up of a protein called amyloid-beta between neurons is…

Evidence mounts for alternate origins of Alzheimer’s disease plaque, as a new experiment in mice reveals that the buildup of debris-filled plaques is preceded by a breakdown in how brain cells rid themselves of waste.Results could explain why drugs designed to remove amyloid deposits have failed to stop disease.According to the National Institute on Aging, <span class="glossaryLink" aria-describedby="tt" data-cmtooltip="<div class=glossaryItemTitle>Alzheimer’s</div><div…