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“Hard To Lose” Mutations in Tumors May Predict Response to Immunotherapy

The figure shows the interactions between immune cells (white) and tumor cells harboring persistent mutations (red) in the context of immunotherapy (white) as a chess match captured in 5 snapshots. The piece placement is pulled from a Kasparov vs Deep Blue game. Credit: Christina Kostandi and Valsamo AnagnostouCancer specialists have attempted to utilize the number of mutations in a tumor, known as the tumor mutation burden (TMB), to forecast a patient’s response to immunotherapy, with varying degrees of success.…

DCU Doomsayers Predict James Gunn Being Extremely Online Could One Day Derail the Franchise

Photo by Frazer Harrison/Getty Images A harsh reality of movie-making is that you can’t please everyone, and (more importantly) if you try to please everyone, you end up pleasing no one at all. Such is the way of show business. In a world where that fact seems to be growing more and more contentious, director James Gunn thankfully understands how an entertainment company should be run these days. Heading up DC Studios with producer Peter Safran, Gunn announced earlier this year his plan for an entirely new…

Study discovers how Apple Watch can predict pain in people with Sickle Cell

We always hear about how the Apple Watch can be an ally to help prevent and discover diseases. While it’s a long journey for Apple to say its smartwatch can help with X or prevent Y, important universities conduct studies to see how the wearable could help physicians and patients better understand the disease they want to prevent or treat. This time, a team of researchers from Duke University, Northwestern University, and others published a paper (via MyHealthyApple) showing how the Apple Watch could help…

Straight from the heart: Mysterious lipids may predict cardiac problems better than cholesterol | Science

A version of this story appeared in Science, Vol 379, Issue 6637.Download PDF Stephanie Blendermann, 65, had good reason to worry about heart disease. Three of her sisters died in their 40s or early 50s from heart attacks, and her father needed surgery to bypass clogged arteries. She also suffered from an autoimmune disorder that results in chronic inflammation and boosts the odds of developing cardiovascular illnesses. “I have an interesting…

Apple Watch could help predict pain among sickle cell disease sufferers, study finds

A study of suffers of sickle cell disease admitted to the Duke University SCD Day Hospital has found that an Apple Watch can be used to help predict pain.The people were given an Apple Watch Series 3 to wear during their stay at the hospital with the study using its sensors to collect data including heart rates, heart rate variability, and heart rate variability.Sickle cell disease is associated with severe complications including chronic anemia, stroke, and vaso-occlusive crises (VOCs), the latter of which can be…

Recently developed AI system can calculate delays and predict hazards, interruptions in aviation

Credit: Pixabay/CC0 Public Domain An AI system has been developed through a project at Mälardalen University (MDU) that can calculate delays and predict hazards and interruptions in aviation. The system will not only be able to assist air traffic controllers to predict and communicate the disruptions to passengers and operators in the aviation industry, but also prevent the actual disruptions.…

New ocean in making? Africa slowly splitting into two, scientists predict nature’s rarest move

New ocean in making? Africa slowly splitting into two, scientists predict nature's rarest move | Photo: Reuters (Image for representation)As Africa splits into two pieces, scientists predict the beginning of the rarest natural phenomena. Researchers believe that in the distant future, the creation of a new ocean may result in the division of Africa into two pieces. The separation of two significant portions of the continent may eventually lead to the formation of a new body of water. In millions of years, landlocked…

Another (Conformal) Way to Predict Probability Distributions | by Harrison Hoffman | Mar, 2023

Conformal multi-quantile regression with CatboostTexas. Image by Author.In a previous article, we explored the capabilities of Catboost’s multi-quantile loss function, which allows for the prediction of multiple quantiles using a single model. This approach elegantly overcomes one of the limitations of traditional quantile regression, which necessitates the development of a separate model for each quantile, or storing the entire training set in the model. However, there is another disadvantage to quantile regression,…

NASA can now predict solar flares!

Solar flares can be very dangerous for the power grid, satellites, even mobile phones. How dangerous a flare can be depends on how powerful it is. If a warning is received by NASA and other space agencies on time, the impact on Earth and humanity can be lessened. Now, NASA has got a solution for the same. Yes, NASA has said that it can predict Solar Flares. Scientists can now predict when and where the Sun's next flare might explode. The crucial role is that of Sun "Flashes".Notably, Solar flares are powerful bursts of