Protein

By University of Pennsylvania School of Engineering and Applied Science February 27, 2024Scientists have introduced CluMPS, a novel molecular tool that simplifies the detection of tiny protein clusters implicated in diseases like Alzheimer’s. This technique allows for easy visualization with standard lab microscopes, overcoming the limitations of light microscopy and facilitating drug efficacy assessment and new treatment discoveries. The development of CluMPS, represents a significant step forward in understanding…

High protein consumption may elevate atherosclerosis risk by activating immune cells that contribute to arterial plaque formation, with leucine playing a critical role, according to a study by the University of Pittsburgh School of Medicine.High protein consumption may elevate atherosclerosis risk by activating immune cells that contribute to arterial plaque formation, with leucine playing a critical role.University of Pittsburgh School of Medicine researchers discovered a molecular mechanism by which excessive dietary…

Research from Tufts University indicates that women who consume more plant-based proteins are less likely to develop chronic diseases and maintain better health into older age. The study, analyzing data from over 48,000 women, highlights the benefits of plant proteins over animal proteins for heart health, mental health, and overall longevity, recommending a diet rich in fruits, vegetables, nuts, and seeds, with some fish and animal protein for essential nutrients.A recent study led by Tufts University discovered that…

Researchers at UC Riverside have made a groundbreaking discovery in cancer treatment by developing a peptide that can control MYC, a key protein involved in the majority of human cancers. This innovation offers new hope for targeting cancer at a molecular level, paving the way for more effective treatments.Discovery paves the way for more effective treatment.Meet MYC, the shapeless protein responsible for making the majority of human cancer cases worse. UC Riverside researchers have found a way to rein it in, offering…

DeepGO-SE, an AI tool created by KAUST researchers, revolutionizes the prediction of unknown protein functions using logical entailment and advanced language models, showing significant potential for scientific research and biotechnological applications. Credit: SciTechDaily.comKAUST’s DeepGO-SE AI tool excels in predicting functions of unknown proteins, offering promising applications in biotechnology and research.A new artificial intelligence (AI) tool that draws logical inferences about the function of unknown proteins…

A groundbreaking study identifies the VAPB gene, previously associated with ALS, as a key player in medulloblastoma, suggesting its potential as a marker and target for therapy in this aggressive childhood brain cancer. This discovery offers new insights into cancer biology and treatment possibilities. Medulloblastoma cells kept in 3D culture (tumor spheroids) or 2D culture at the researchers’ lab. Credit: Amanda Faria AssoniA protein, extensively researched for its connection to neurodegenerative disorders like…

Researchers at City of Hope have identified a crucial interaction between two proteins that facilitate cancer cell growth, offering a new target for developing effective cancer treatments. Credit: SciTechDaily.comScientists identify treatment target that disrupts proteins’ interaction, offering hope for new therapeutic approach.Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have discovered a new cellular mechanism that plays an important role in cancer…

A groundbreaking study by the University of Copenhagen has unveiled the properties of all 28,000 human disordered proteins, challenging traditional protein structure concepts and offering new insights into their role in diseases. Credit: SciTechDaily.comResearch reveals new insights into 28,000 human disordered proteins, altering our understanding of protein structures and functions.Protein molecules lie at the heart of biology. Our typical understanding of proteins states that each type of protein has a specific…

The protein MYC is part of healthy cell activity, but when cancer cells develop, it goes haywire – going outside of its normal, carefully controlled role and helping cancer to spread. Now, scientists may have found a way to stop this from happening.Part of the problem in reining in MYC is that it's a shapeless protein, one that doesn't really have a structure that can be targeted. That makes it difficult for drugs to effectively identify MYC and keep it behaving normally.However, a team from the University of California,…

Human cells showing cell nuclei (cyan), mitochondria (magenta), and the Coxiella burnetii protein MceF (yellow). The figure evidences the co-location of MceF with cellular mitochondria. Credit: Robson Kriiger LoterioResearchers have discovered a previously unidentified protein with antioxidant properties produced by Coxiella burnetii, a Gram-negative intracellular bacterium. This breakthrough suggests potential new treatments for autoimmune diseases and cancer.Researchers at the University of São Paulo, in collaboration…