Rockefeller University

New research utilizing advanced imaging to track one million neurons in mice uncovers that over 90% of brain activity, previously considered noise, contains significant signals, revealing the mammalian brain’s underestimated complexity. Credit: SciTechDaily.comThe mammalian brain is a web of densely interconnected neurons, yet one of the mysteries in neuroscience is how tools that capture relatively few components of brain activity have allowed scientists to predict behavior in mice. It is hard to believe that much of the…

Hair follicle stem cells (green) mobilize and expand (white) to help repair the skin’s barrier by differentiating into epidermal lineages (red). Credit: Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development at The Rockefeller UniversityWhen a child falls off her bike and scrapes her knee, skin stem cells rush to the rescue, growing new epidermis to cover the wound. However, only a portion of these stem cells, which eventually repair the damage, are typically assigned the task of replenishing the…

Discoveries about the end-replication problem indicate both telomerase and the CST–Polα-primase complex are essential for chromosome protection, suggesting a revision in the science of telomeres and potential impacts on genetic disorders. Credit: SciTechDaily.comRecent research challenges the long-standing understanding of the end-replication problem in DNA, revealing two distinct issues rather than one.Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how…