stubborn

A single injection of the 102-year-old tuberculosis vaccine, BCG, has proven effective at triggering an immune response in mice and shrank their liver cancer tumors, according to research by UC Davis Health. The findings suggest that BCG might be an alternative way of treating this notoriously hard-to-treat cancer.As the most common type of liver cancer, hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. Despite treatment options that include surgery, radio- and chemotherapy,…

Using a cold plasma jet to activate hydrogel, researchers have created a dressing with antibacterial and wound-healing properties. The technology could be used as an alternative to current treatments that rely on antibiotics to treat chronic wounds, such as diabetic foot ulcers.The growing global number of diabetics means that there will be more people who experience a foot ulcer in their lifetime. For 60% of diabetics, these ulcers will become infected, and because of poor wound healing associated with the condition, the…

With every new day, I personally become convinced that problems in people’s family lives can be caused by literally any reason. From discrepancies in culinary tastes to differences in views on raising children and, in general, plans for their birth. From political or sports beliefs to disagreements regarding what spouses will call each other in public.Yes, this is also becoming a source of serious controversy – so here’s today’s story from the user u/Throwaway_partner1 in the AITAH community on Reddit. And, by the way,…

In what has already been tagged as a “game-changer” for cancer treatment, the potent once-a-day tablet known as divarasib has continued to impress at Phase 1b trial stage, outperforming not just current therapies but its previous trial results.Following on from a standalone clinical trial earlier this year, divarasib has now been combined with the existing targeted immunotherapy drug cetuximab, and has delivered a 62.5% positive outcome for people with advanced or metastatic colorectal cancer (CRC) linked to the KRAS G12C…

Cillian Murphy is struggling with what he can and can’t say about his title role in Oppenheimer, the latest Christopher Nolan epic, such is the secrecy surrounding this film. Murphy is under “strict instructions” not to talk about the content. Which is awkward when you’ve flown to his home in Ireland to interview him specifically about playing the physicist who oversaw the creation of the atomic bomb, later detonated over Hiroshima and Nagasaki. It’s not clear who issued these instructions. Nolan? The studio? The US…

When Russian troops approached the small farming town of Voznesensk, they were not expecting a battle. A week earlier, Vladimir Putin’s full-scale invasion of Ukraine had begun. An armoured column trundled insouciantly across a landscape of southern fields and villages. The goal was to capture a crossing point between two rivers. From there the Russians would roll to Odesa, the twinkling Black Sea port.Standing in the way of this mighty army was a motley group of Ukrainian defenders. They included a few soldiers and 30…

Federal Reserve Bank of Cleveland President Loretta Mester said Tuesday inflation remains too high and stubborn, and that it could take until 2025 to bring it down to the Fed’s 2% target. Ms. Mester also reiterated the Fed’s resolve to fight inflation while the central bank contends with the fallout of the collapse of Silicon Valley Bank last month. “The... Federal Reserve Bank of Cleveland President Loretta Mester said Tuesday inflation remains too high and stubborn, and that it could take…

Mathematicians wanted to better understand these numbers that so closely resemble the most fundamental objects in number theory, the primes. It turned out that in 1899—a decade before Carmichael’s result—another mathematician, Alwin Korselt, had come up with an equivalent definition. He simply hadn’t known if there were any numbers that fit the bill.According to Korselt’s criterion, a number N is a Carmichael number if and only if it satisfies three properties. First, it must have more than one prime factor. Second, no…

If you have an application that is no longer responding, click the Apple menu at the top left corner of the desktop, and select Force Quit.  You can force-quit any user-facing app in MacOS with the Force Quit tool. Image: Jack WallenAlso: How to delete apps on your MacBook in 3 steps The command line method You might not know this, but MacOS is very much in line with Linux on many levels. For instance, MacOS includes a powerful command line tool that can simplify a lot of tasks… even killing rogue…

Credit: Unsplash/CC0 Public Domain A new study from researchers at the University of Wisconsin-Madison shows why letting stereotypes inform our judgments of unfamiliar people can be such a hard habit to break. …