Antibiotic

Today is Christmas and, as expected, most businesses and governments have shut down for the day and people are enjoying a holiday. Yet artificial intelligence developments have found a way to emerge even today. In a shocking development, the parent company of Paytm, One97 Communication, has fired more than 1000 employees. The underlying reason behind the Paytm layoff is reported to be the AI advancement of the company that has caused a few positions to be surplus to requirements. This and more in today's AI roundup. Let…

The urgent crisis of antibiotic-resistant superbugs is addressed in groundbreaking research by UMass Amherst and Microbiotix. Their study, focusing on disrupting the Type 3 secretion system of pathogens, offers a novel approach to preventing infections. This strategy, supported by innovative luciferase-based techniques, paves the way for new drugs and enhances our understanding of microbial infections, marking a significant advance in public health. Credit: SciTechDaily.comTeam develops test to identify new drugs that can…

A new study has found that using a digital support algorithm to guide diagnosis and treatment by healthcare providers significantly reduced the number of antibiotic prescriptions given to acutely sick children, without affecting treatment success or causing harm.The rising worldwide problem of bacterial antimicrobial resistance (AMR) is well-known, leading to a population of pathogens resistant to antibiotic treatment. One of the primary contributors is the inappropriate and excessive prescription of…

Maynooth University researchers have discovered a novel molecule to fight drug-resistant bacteria, leveraging supramolecular chemistry. The new findings offer a potential new approach to antibiotic development, with significant implications for public health. Credit: Ella Maru StudiosResearchers at Maynooth University have developed a new molecule designed to combat drug-resistant bacteria.An international team, including researchers from Maynooth University, has developed a novel molecule with the potential to combat…

A research team has found that Nourseothricin, an old antibiotic, could be effective against drug-resistant bacteria. Improved purification techniques have identified less toxic forms of the antibiotic, specifically Streptothricin-F, that show strong activity against Gram-negative bacteria, by binding to a bacterial ribosome subunit and inducing translation errors, offering a unique approach to combating such infections.Better purification overcomes original renal toxicity concerns.An old antibiotic could potentially…

The antibiotic Recarbrio was approved by the FDA despite serious doubts about its effectiveness and high cost compared to a generic alternative. The FDA reportedly bypassed its own standards of requiring “substantial evidence” of a drug’s effectiveness for approval, triggering concerns about the agency’s internal issues and potential erosion of safety and effectiveness standards.Has the recently developed antibiotic met the legal standard for approval? Are the regulations of the US drug regulatory system being…

The long-running saga over a Washington woman’s refusal to get treated for tuberculosis might finally be drawing to a close. The woman was released from a local jail late last week, under the condition that she stay isolated at home and complete her course of antibiotics. Should she fail to do so, she could be arrested yet again.Are Big Consumer Facing Tech Companies Redeemable? The Tacoma-Pierce County resident—identified only as V.N. in court documents—has been knowingly infected with the bacterial disease for quite…

Staphylococcus aureus is a Gram-positive bacterium commonly found on the skin and nasal passages of humans. While it is a normal part of the human microbiota, it can also cause a range of infections, from minor skin infections to life-threatening conditions such as pneumonia and bloodstream infections. This bacterium is known for its ability to develop antibiotic resistance, making it a significant concern in healthcare settings.Staphylococcus aureus is a common bacterium that you may have encountered if you’ve ever had a…

AI technology has helped MIT and McMaster University researchers identify a new antibiotic named abaucin, effective against Acinetobacter baumannii, a hospital-borne, drug-resistant bacteria. The drug, discovered through a machine-learning model, is significant due to its narrow-spectrum efficacy and unique mechanism of disrupting lipoprotein trafficking within bacterial cells.The machine-learning algorithm identified a compound that kills Acinetobacter baumannii, a bacterium that lurks in many hospital settings.Using an…

Just as antibiotic resistance is a problem for human health, herbicide resistance represents a huge problem for the agricultural sector. Researchers have devised a novel strategy to address the issue by repurposing a "failed" antibiotic as a herbicide.Farmers have a lot to contend with when it comes to protecting their crops: the insects that eat the plants, the microbes that infect leaves, shoots, and roots, and invasive weeds that compete with crops for soil and Sun.Herbicide options are decreasing because of the spread…