Antibiotic

GSK GSK -0.79% PLC said its experimental treatment for uncomplicated urinary-tract infections was effective in two large clinical trials, paving the way for what could be the first new oral antibiotic for the common ailment in more than two decades. Around half of all women have suffered a urinary-tract infection, or UTI, at least once, and recurrence is common, according to studies. UTIs are typically treated with antibiotics, but…

Toronto, November 1 Triclosan, a chemical often included in household items like hand soaps, toothpastes and cleaning products to fight off bacteria, has now been linked to antibiotic resistance. According to the study by assistant professor Hui Peng's research group at University of Toronto, among thousands of co-occurring chemicals in the sludge, triclosan was found to be the predominant antibacterial compound impacting E coli. Antibiotic-resistant bacteria -- also…

Procedures such as knee and hip replacements can expose patients to potential bacterial infections, and bone cements are one way physicians can lower the risk. These materials anchor the artificial joint in place and, if loaded with antibiotics, can protect against harmful bacteria at the site. But the rise of drug-resistant bacteria calls for new approaches to these types of problems, and a potent new form of bone cement is poised to take up the fight.“Currently, the Food and Drug Administration (FDA) has only approved…

A new research conducted by the The Lancet Regional Health-Southeast Asia has found out that Azithromycin 500mg tablet was the most consumed antibiotic formulation (7.6 per cent) in India, followed by cefixime 200 mg tablet (6.5 per cent) .…

A huge analysis looking at thousands of strains of tuberculosis bacteria has found new genes linked to antibiotic resistance – discoveries that could play a crucial role in the future treatment and prevention of tuberculosis, and the fight against drug-resistant bugs.Right now, tuberculosis (TB) can be prevented with a vaccine, and in most cases cured through six months of drug treatments. However, it still claims around 1.5 million lives globally every year – and we don't want that number going in the wrong…

Bacteria are fast developing resistance to our best drugs, leaving us poised on the edge of a major health crisis. But a new antibiotic has shown promise against several key “superbugs,” while minimizing damage against good bacteria in the body.Bacteria are a textbook example of evolution in action. When they face environmental hazards – such as antibiotics – only the strongest survive to replicate, meaning that eventually the entire population has the ability to resist drugs. A class known as gram-negative bacteria are…

As antibiotic-resistant bacteria become increasingly challenging to defeat, consulting those who've been in battle with our ancient foe long before us just makes a whole lot of sense.   Viruses called bacteriophages have been clashing with bacteria since long before we even existed. So researchers from the University of California, San Diego, took a closer look at some of the lesser studied jumbo phages, specifically 201phi2-1, which infects Pseudomonas chlororaphis bacteria.Named for their large genomes of over 200,000…

A new study has shown that taking a single dose of a widely used, cheap antibiotic within 3 days after condomless sex can help prevent chlamydia, syphilis, and gonorrhea, three sexually transmitted infections (STIs, also referred to as sexually transmitted diseases or STDs) that have soared in the United States, Europe, and elsewhere over the past 2 decades. The study, mainly in men who have sex with men (MSM) in San Francisco and Seattle, was halted in May after an independent…

Karen Hopkin: This is Scientific American’s 60-Second Science. I’m Karen Hopkin. Hedgehogs are a lot of things. They’re small and spiky, covered in quills. And some people even say they’re cute. Now, a new study says that they are also the origin of resistance to methicillin, an antibiotic derived from penicillin. That pointed observation appears in the journal Nature. Antibiotic resistance is a huge clinical problem. And methicillin-resistant Staphylococcus aureus…otherwise known as M-R-S-A or MRSA…can be difficult to…

Researchers, looking to identify potential antiviral therapies that are effective against COVID-19, found that the antibiotic clofoctol may be an effective treatment for SARS-CoV-2 infections in mice.Study in mice suggests Clofoctol inhibits <span class="glossaryLink" aria-describedby="tt" data-cmtooltip="<div class=glossaryItemTitle>SARS-CoV-2</div><div class=glossaryItemBody>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the official name of the virus strain…