bowel

Researchers have created model tumors using the tissues of patients with advanced bowel cancer and used them to predict how the disease will respond to specific drug therapies – before treatment begins. Found to be 83% accurate, the pioneering approach would increase the chances that patients receive the most effective treatment at the earliest opportunity.Bowel cancer is the second leading cause of cancer-related death worldwide despite an increasing number of treatment options. If caught early enough, the cancer can be…

Researchers have modified a unique cancer-loving probiotic bacteria to release a marker that can be detected in the urine after it comes into contact with bowel cancer, even when it's in the early stages. The novel test may mean avoiding invasive procedures like colonoscopies and messy poo-based screening tests.Globally, colorectal cancer – also known as bowel cancer – is the second leading cause of cancer-related death, with a concerning rise in incidence rates in younger populations, highlighting the importance of early…

Researchers have revealed how aspirin inhibits colorectal cancer by activating tumor-suppressing microRNAs, offering potential for its use as a preventive and therapeutic agent, especially in cancers where the p53 pathway is compromised.Researchers at LMU have discovered a signaling pathway through which aspirin can can inhibit colorectal cancer.Colorectal cancer, also known as bowel cancer, ranks as the world’s third most prevalent cancer type, with approximately 1.9 million new cases and 900,000 fatalities annually.…

In an extensive study at the University of California, Riverside, researchers have found that high consumption of soybean oil can lead to an increase in harmful bacteria in the gut, potentially causing colitis and IBD. The linoleic acid in soybean oil was identified as the primary concern, with researchers observing that excess amounts negatively affect the gut microbiome.UC Riverside-led mouse study reports diets high in soybean oil decrease endocannabinoids in the gut and can lead to colitis.High consumption of soybean…

Perianal Crohn’s disease is a type of inflammatory bowel disease that affects the area around the anus. It can cause symptoms such as pain, itching, and discharge, as well as more serious complications such as abscesses and fistulas.Scientists at Cedars-Sinai have identified a genetic variant that is associated with perianal Crohn’s disease.Investigators at Cedars-Sinai have discovered a genetic variant that elevates an individual’s likelihood of experiencing perianal Crohn’s disease, which is considered to be the most…

Irritable Bowel Syndrome (IBS) is a common gastrointestinal disorder that affects the large intestine. It is characterized by symptoms such as abdominal pain, bloating, constipation, and diarrhea.According to a team of Korean researchers, individuals with Irritable Bowel Syndrome (IBS) have a decreased diversity of bacteria in their intestines compared to healthy individuals. This is the first study to establish a clear connection between IBS and a reduction in gut microbiota diversity. The findings were published in the…

Inflammatory Bowel Disease (IBD) is a group of chronic disorders that cause inflammation in the digestive tract, including the small intestine and colon. IBD can cause symptoms such as abdominal pain, diarrhea, and weight loss.Frequent antibiotics use may increase the risk of developing inflammatory bowel disease for adults over 40, according to research published in the journal Gut. The study suggests that individuals taking antibiotics for gut infections have a higher risk, with the risk being greatest 1-2 years after…

Regular consumption of a common synthetic food dye widely used in sweets, soft drinks, and cereals could be impacting our gut health – and not in a good way.A new study on mice suggests the colorant Allura Red AC can trigger inflammation of the large intestine if eaten regularly. When consumed by younger mice, it appeared to enhance the risk of developing gut issues later on.'Regular' in this instance means daily exposure, something that might only apply to hardcore fans of colored candies and vibrant breakfast cereals.…

Researchers say that consumption of Allura Red food dye over the long term can be a potential trigger of inflammatory bowel diseases (IBDs), Crohn’s disease, and ulcerative colitis. This food dye is a common ingredient in candies, soft drinks, dairy products, and some cereals.Scientists found that continual exposure to Allura Red AC harms gut health and promotes inflammation.Allura Red (also called FD&C Red 40 and Food Red 17), is a common ingredient in food ranging from candies and soft drinks to dairy products and…

According to a new study from Cedars-Sinai Medical Center, irritable bowel syndrome may be caused by gravity.New hypothesis unifies several contrasting theories that may help explain the underlying cause of IBS.According to a new theory from researchers out of Cedars-Sinai Medical Center, gravity may be the cause of irritable bowel syndrome (IBS), the most common gastrointestinal disorder.Brennan Spiegel, MD, MSHS, director of Health Services Research at Cedars-Sinai and author of the hypothesis, explains that IBS—and…