Cells

The Expedition 70 crew at the International Space Station embarked on a busy week filled with stem cell research and preparations for the arrival of the Progress 87 cargo craft.A busy week of science and prep for an upcoming cargo delivery kicked off aboard the International Space Station on Monday as the Expedition 70 crew set its sights on new stem cell research and orbital training.Preparation for Cargo DeliveryTwo cosmonauts, Flight Engineers Oleg Kononenko and Nikolai Chub, are gearing up to be on duty monitoring the…

Scientists have identified a mutation that significantly boosts the cancer-fighting ability of engineered T cells without causing toxicity. This innovative approach, which works against multiple tumor types in mice, could lead to effective treatments for previously incurable cancers and is advancing toward human trials. Credit: SciTechDaily.comResearchers have engineered T cells with a cancer-derived mutation, boosting their potency against tumors over 100-fold without toxicity, marking a significant advancement in…

Dead Cells designer Sébastien Benard has hit out at Motion Twin for its decision to stop updating the roguelike-Metroidvania game. Following the success of Dead Cells in 2018, Motion Twin set up separate studio Evil Empire in 2019 to focus on updating the game, allowing Motion Twin to work on new projects. However, last week a statement confirmed that the upcoming Update 35 would be the last. The update “marks the end of our creative journey on the game” said Motion Twin. “Our commitment to avoiding the ‘more of the…

Acute myeloid leukemia (AML) isn’t the most commonly known cancer. It is, however, one of the deadliest—an awful rare malignancy of the blood and bone marrow whose victims are already older and frail, on average 68 years old when diagnosed. It has few treatment options—chemotherapy is most common, according to the American Cancer Society—and any available ones must be deployed immediately after it’s diagnosed given how rapidly this aggressive cancer spreads. Nearly 70% of AML patients die within five years of diagnosis,…

Developers Evil Empire and Motion Twin have announced that update 35 for Dead Cells, called "The End is Near," will be the last one that adds new content, bringing an end to five years of post-launch support.The decision to end the journey was made in order to prevent future updates from feeling derivative. "Our commitment to avoiding the 'more of the same' trap and keeping Dead Cells fresh and original has led us to this point," Motion Twin explained in a statement. "As we've seen with other long-running…

The highly acclaimed indie roguelite side-scroller, Dead Cells, is about to wrap up shop, from the looks of it. While it’s been known for some time now that Dead Cells‘ Update 35 will be fairly sizeable, Motion Twin has just announced it’ll also be the game’s final content update. According to Motion Twin’s latest Dead Cells blog post on Steam, “Update 35 for Dead Cells marks the end of creative journey on the game.” Having been released from Steam’s Early Access program back in 2018, Dead Cells has received dozens of…

New research has uncovered the mechanism by which amino acids activate TORC1, a key protein in cell growth and autophagy. The research reveals that cysteine activates TORC1 via the Pib2 protein and highlights the varied influences of all 20 amino acids on TORC1 through two pathways. This discovery offers new insights into cellular processes and potential treatments for diseases linked to TORC1 malfunctions.Researchers at Osaka University uncover the mechanism by which cysteine activates a crucial regulator of cell growth…

If you ask anyone who’s actually what the best feature is, they’ll likely call out the dual micro-OLED displays. These screens produce especially crisp visuals, and iFixit has taken it upon themselves to find out why. The publication with an emphasis on those glorious displays.The big takeaway? The screens are incredibly pixel-dense, with 12,078,000 pixels smushed into 0.98 square inches. This means that each individual pixel is just 7.5 μm, which makes them Yeah. The ones in our bodies right now.This is much more…

A groundbreaking study by LJI scientists has uncovered how T cells target Mycobacterium tuberculosis, identifying key T cell epitopes that could lead to new TB vaccines and diagnostics. This research offers hope for more effective TB treatments and preventative measures.By tracking T cell activity, researchers uncover promising tuberculosis vaccine and drug targets.La Jolla Institute for Immunology (LJI) is working to guide the development of new tuberculosis vaccines and drug therapies.Now a team of LJI scientists has…

It’s crazy to think of how far video games have come since the original Doom release in 1993. But, as iconic of a game as it is, what has even become more iconic than the game itself is getting it to run on tons of different things. In fact, we’ve seen Doom play on a myriad of things. And now, some scientists have even managed to run Doom on E. coli cells.Yes, you read that correctly. An MIT doctoral candidate by the name of Lauren “Ren” Ramlan has shared video proof of Doom running on cells. Ramlan admitted…