Columbia Researchers Discover Rare Lipids Triggering Cell Death
Illustration of a diPUFA phospholipid, a type of lipid with two polyunsaturated fatty acyl tails, breaking through a cell’s outer lipid layer as the cell dies. New research has shown that diPUFA phospholipids are a key driver of a form of cell death known as ferroptosis. Credit: Nicoletta Barolini/Columbia UniversityScientists have discovered that a rare lipid type plays a pivotal role in ferroptosis, a form of cell death. This finding sheds light on the mechanisms of cell death in ferroptosis and opens up possibilities…