diabetes

Recent research led by Indiana University and the University of Chicago Medicine suggests that the drug α-difluoromethylornithine (DFMO) could revolutionize type 1 diabetes treatment. Building on a decade of studies, DFMO has demonstrated potential in reducing insulin dependency and is now being tested in a larger clinical trial to assess its impact on beta cell preservation and disease modification.Recent research led by Indiana University School of Medicine in collaboration with the University of Chicago Medicine…

A chronic condition that occurs when the pancreas stops making insulin (type 1) or the body can’t effectively use the insulin it makes (type 2), diabetes can lead to a raft of complications. The disease, which affects hundreds of millions of people globally, was the focus of much research in 2023, resulting in a few ‘world-firsts’. From trialing a diabetes-slowing tablet to using plant extracts and creepy crawlies to lower blood sugars, here are the year’s top diabetes stories to grace our pages over the past…

A Cochrane review reveals that certain types of insulin can be stored effectively at room temperature for months, offering a practical solution for diabetes care in regions without stable refrigeration.A recent Cochrane review has revealed that insulin retains its effectiveness even when stored at room temperature for extended periods. This discovery is particularly significant for individuals with diabetes living in areas with limited access to healthcare or stable powered refrigeration.A recent Cochrane review reveals…

Stanford engineers have developed an injectable hydrogel depot technology that enables GLP-1 drugs to be administered once every four months, compared to repeated daily injections. Credit: Photo courtesy of Andrea Ivana d’Aquino / Stanford UniversityInnovations in Type 2 diabetes treatment have been revolutionized by dietary management drugs, although the requirement for daily injections poses difficulties for some individuals. A new hydrogel could mean shots just three times a year.Materials engineers at Stanford…

More than half a billion people worldwide are affected by type 2 diabetes, and yet researchers still don't know what's behind the condition's breakdown in insulin functionality.Researchers from Case Western Reserve University in the US have now pulled back the molecular curtain and figured out why insulin, the hormone that maintains stable blood sugar, often stops working at its full effect.The principal investigator, Jonathan Stamler, is widely acclaimed for the discovery of S-nitrosylation, which is the process that…

Your snack habit may be even more calorie-dense than you think, recent research suggests. A study estimated that snacking contributes to around 20% of an average American’s daily caloric intake, and these snacks often add little nutritional value. The scientists found, though, that people with type 2 diabetes seem to eat fewer snack-related calories.Google’s AI Isn’t a Gimmick, It’s the Future | AI UnlockedThe study was led by scientists from The Ohio State University. Research has consistently shown that Americans’ diets…

New research has established a direct link between high insulin levels in patients with obesity and Type 2 diabetes and an increased risk of pancreatic cancer. This groundbreaking study demonstrates how excess insulin overstimulates pancreatic acinar cells, leading to inflammation and precancerous cells, particularly in the case of pancreatic ductal adenocarcinoma (PDAC). These findings highlight the importance of maintaining healthy insulin levels and may lead to new strategies for cancer prevention and treatment,…

New research reveals a significant link between nutrition, diabetes, and mental health. Poor dietary choices contribute to the risk of developing type 2 diabetes and mental health issues like depression and anxiety. Conversely, diets rich in essential nutrients and low in processed foods can reduce these risks. The findings highlight the importance of informed dietary choices in managing and preventing diabetes, anxiety, and depression, suggesting implications for public health policies and healthcare practices.New…

New research shows that tirzepatide, the latest FDA-approved obesity drug, really can help people lose substantial amounts of weight—but only if they continue taking it. The study found that people who stopped taking tirzepatide after 36 weeks regained much of their lost weight within a year, while those who continued to take it lost even more, about 25% of their original weight on average.'Even AI Rappers are Harassed by Police' | AI UnlockedTirzepatide was developed by Eli Lilly and was first approved in 2022 by the…

Scientists have discovered a new mechanism for how type 2 diabetes takes hold, and demonstrated in mice that blocking a particular enzyme could open a new avenue of treatment for the disease.Type 2 diabetes begins as a patient’s body stops responding to insulin, and eventually loses the ability to produce enough of the hormone. Without it, blood glucose levels remain high and can cause a range of serious health problems. But scientists still don’t fully understand exactly why the insulin system stops working in the first…