Ebola

The candidate that’s farthest along is the single-dose ChAd3 Ebola Sudan vaccine, which is being developed by the Sabin Vaccine Institute, a nonprofit based in Washington, DC. By working with the World Health Organization (WHO), the Coalition for Epidemic Preparedness Innovations, and other organizations, the institute is planning to run a clinical trial in the current outbreak to see how well the vaccine works.But there are only 100 doses available. With limited supply, health officials plan to give doses of the vaccine…

A 24-year-old man who tested positive for Ebola virus disease caused by Sudan ebolavirus (SUDV) was the first confirmed case in Uganda’s ongoing Ebola outbreak, but health authorities believe he was probably not the initial, or index, case. As of October 9, confirmed cases totaled 48, with 17 deaths, according to the Ministry of Health Uganda. But those numbers will likely continue to rise. Uganda’s health authorities officially declared the outbreak on September 20. An approved vaccine for Ebola exists, but it is not…

A multipronged international effort has begun to pull out all the stops to launch trials of experimental Ebola vaccines in Uganda, which declared an outbreak of the deadly disease on 20 September. According to the most recent World Health Organization (WHO) update, Uganda has had 18 confirmed and 18 suspected cases of Ebola, including 23 deaths—an unusually high case fatality rate of 64%. A trial of a vaccine candidate that’s farthest along in development could launch before…

The WHO on Saturday declared the surge in monkeypox to be a PHEIC after experts reviewed the situation at an emergency committee meeting two days earlier. Here is a look at how the decision is made and previous PHEIC declarations: What is a PHEIC? The conditions which must be met are set out under the 2005 International Health Regulations (IHR) -- the legal framework defining countries' rights and obligations in handling…

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