genomics

An administrative law judge has ruled in favor of Illumina Inc. ILMN -3.10% in its $7.1 billion acquisition of cancer-testing developer Grail Inc., dealing a defeat to the Federal Trade Commission’s efforts to unwind the deal on antitrust grounds, the company said. Illumina said the judge rejected the FTC’s position that the deal would hurt competition in the market for multicancer early-detection tests. “As we’ve stated…

Some of the lookalike pairs who were studied in the current research.Photo: Joshi, et al/Cell ReportsIt turns out that unrelated doppelgangers may have quite a bit in common beyond just twin faces. New research suggests that lookalikes with incredibly similar faces tend to share many genetic variants—variants that don’t seem to just shape their appearance but general aspects of their life. At the same time, other important influences, such as the microbiome, appear to contribute little to their symmetry.Study author Manel…

They added the chemical that triggered the first gene (corresponding to barcode A) for 24 hours, followed by the one for the second gene (corresponding to barcode B) for the next 24. “In theory we should have all the recording proteins turned on throughout the process, but only the RNA for signal A in the first half and signal B in the second half,” Bhattarai-Kline says.When the scientists sequenced the E. Coli’s genomes, that’s exactly what they found: The DNA receipts for barcode A were integrated into the Crispr array…

Genetics is the study of inheritance—from someone’s brown eyes to their inability to eat dairy. Taken together with genomics—the study of the entire genome of an organism—researchers get better at understanding overall human health, and how to fight diseases. Genetics and genomics will pave the way for innovations in health and better understanding of human origins. “There’s just no question that 30 years ago, if you would have told me how far genomics would be in 2022, I would have just said, you’re out of your mind,…

Recent research analyzes mathematical models created to deduce conclusions about how evolution works at the level of populations of organisms.A study examines the benefits and drawbacks of evolutionary genomics.Claudius Ptolemy, an astronomer and mathematician from Alexandria in the second century, had a lofty goal. He wrote the Almagest, a magisterial treatise that attempts to explain the motion of stars and the motions of planets. Ptolemy devised a sophisticated mathematical universe model that seemed to replicate the…

“We didn't see any indication of their drinking coming back to baseline, so we think that maybe this epigenetic editing will produce a long-lasting effect,” Pandey says. “I think a lot more work needs to be done in terms of how this can be translated into humans for a therapy, but I have high hopes.”To test that the Arc gene was truly responsible for this outcome, the researchers also designed a Crispr injection meant to decrease its expression. They tested it in rats that weren’t exposed to alcohol in adolescence.…

As wildly diverse as life on Earth is—whether it’s a jaguar hunting down a deer in the Amazon, an orchid vine spiraling around a tree in the Congo, primitive cells growing in boiling hot springs in Canada, or a stockbroker sipping coffee on Wall Street—at the genetic level, it all plays by the same rules. Four chemical letters, or nucleotide bases, spell out 64 three-letter “words” called codons, each of which stands for one of 20 amino acids. When amino acids are strung together in keeping with these encoded…