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In this Feb. 9, 2021 file photo, a passer-by walks past a sign offering directions to an Uber and Lyft ride pickup location at Logan International Airport, in Boston. Lyft and Uber are threatening to halt operations in Minneapolis because of a city ordinance to increase wages for app-based drivers, the latest back-and-forth that underscores a longtime fight between gig economy workers and the tech giants.Credit: AP Photo/Steven Senne, File…

Researchers at the University of Colorado Anschutz Medical Campus have discovered that inhibiting the Mdm2 protein with a drug called nutlin prevents the synaptic destruction associated with Alzheimer’s disease, offering a promising new avenue for therapy. This approach, which diverges from traditional strategies focusing on amyloid plaque removal, could potentially halt the disease’s progression and is set to undergo further testing in animal models.Researchers at CU Anschutz have discovered a new potential method to…

As It Happens6:08This rare loon brought the Bellagio Hotel's famous Vegas fountain show to a haltWhile it's common to see crowds of people gathered outside the Bellagio Hotel & Casino in Las Vegas, they're not usually there for birdwatching. But recently, a rare juvenile yellow-billed loon took up residence in the hotel's artificial lake, putting the Bellagio's famous fountain show on temporary hiatus. "He's been big news for the last week," Kurt Buzard, senior recreation assistant at the Henderson Bird Viewing…

Odysseus, the first U.S. spacecraft to land on the moon in half a century, was expected to go dark on Wednesday, six days after an off-kilter touchdown that hindered its communications and solar-charging capability, NASA and the company that flew the vehicle said.Despite persistent difficulties in communicating with the lander and keeping it charged, NASA said it managed to extract data from all of its science payloads delivered to the lunar surface by the lander, flown by Texas-based Intuitive Machines."We have conducted…

Bright staining highlights VIP-expressing interneurons in this coronal cross-section of a mouse brain. The neurons may help drive glymphatic clearance of amyloid via the release of peptides. Credit: Tsai Laboratory/MIT Picower InstituteActivating a specific brain wave through light and sound therapy enhances the release of peptides from interneurons, promoting the removal of Alzheimer’s-related proteins through the brain’s glymphatic system, according to recent research.Research from MIT and other institutions is…

Fisker has announced its future plans alongside preliminary 2023 and Q4 earnings, and it's not looking great for the EV manufacturer. The company plans to lay off 15 percent of its workforce — nearly 200 people — as it shifts from a direct-to-consumer to a Dealer Partner model. The company is halting all investments in upcoming models and will resume only if in partnership with another automaker.The company's fourth-quarter revenue increased to $200.1 million from $128.3 million in Q3. However, its gross margin was…

Ever since the COVID-19 pandemic kicked off, we've been far more aware of our sense of smell. Now, new research shows that odors – like those emanating from ripening fruits or fermented foods – can lead to changes in how genes are expressed inside cells far beyond the nose.The findings have scientists wondering if, with much more research, sniffing volatile, airborne compounds could be a way to treat cancer or slow neurodegenerative disease.While the idea of delivering medicine via the nose is not some new idea, that's…

A drug already used to alleviate some of the painful symptoms of rheumatoid arthritis might also be effective at stopping it from developing to begin with – potentially saving millions of people from this debilitating condition.The drug in question is abatacept, and it's been part of a trial set up to test its effectiveness and safety. This involved 213 patients at high risk of developing rheumatoid arthritis in the future, based on early symptoms such as joint pain.For the phase 2b clinical trial, 110 participants were…

India's state-run social security fund will halt claims made via Paytm Payments Bank accounts from Feb. 23, as the country's central bank imposed restrictions on the payments bank due to persistent irregularities, a government order said.The Employees' Provident Fund Organisation (EPFO) has asked its officers to refrain from accepting claims linked with accounts in Paytm Payments Bank, an associate of One 97 Communications, according to the order, which was reviewed by Reuters.The order was issued…

Scientists in Australia think they have discovered a better way to treat the deadliest and most aggressive form of breast cancer.Unlike chemotherapy, the new treatment approach kills and slows the growth of only cancerous cells within breast tissue, not normal, healthy ones.The oral medicine also targets metastatic lesions that have spread elsewhere in the body and show resistance to chemotherapy.Triple-negative breast cancer accounts for up to 15 percent of all breast cancers, and it is notorious for growing and…