The Quest for Chromosome Immortality
Discoveries about the end-replication problem indicate both telomerase and the CST–Polα-primase complex are essential for chromosome protection, suggesting a revision in the science of telomeres and potential impacts on genetic disorders. Credit: SciTechDaily.comRecent research challenges the long-standing understanding of the end-replication problem in DNA, revealing two distinct issues rather than one.Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how…