immune system

A novel treatment method developed by researchers targets lung cancer cells with unprecedented precision, using nanoparticles to deliver chemotherapy drugs directly, potentially transforming cancer care by reducing side effects and improving treatment outcomes.Technique employs patient’s own cells as a Trojan horse to deliver cancer-destroying medications directly to tumors.While lung cancer may not be the most common type of cancer, but it is by far the deadliest.Despite treatments such as surgery, radiation therapy, and…

A tetramer of the influenza neuraminidase protein (shown in blue and light blue) bound by variable domains of two new human antibodies (shown purple/pink and brown/beige) targeting its “dark side.” Viewed along with a 4-fold axis of NA tetramer with its catalytic sites facing up. Credit: NIAIDScientists at the National Institutes of Health have discovered antibodies that attack a difficult-to-detect area of the influenza virus, shedding light on the relatively unexplored “dark side” of the neuraminidase (NA) protein head.…

A study on a man with over 200 COVID-19 vaccinations revealed a fully functional and even enhanced immune response, debunking the theory that excessive vaccination weakens immunity, as shown in research findings published in The Lancet Infectious Diseases.Researchers at FAU have discovered no negative effects on the immune system.Scientists at Friedrich-Alexander University Erlangen-Nürnberg (FAU) and Erlangen University Hospital have studied a man who has undergone over 200 Covid-19 vaccinations. They learned of his case…

Researchers have introduced a groundbreaking CRISPR technology to boost the immune system’s ability to detect and destroy cancer cells. By increasing MHC class I molecules on cancer cells, the new method, dubbed the TRED-I system, shows promise in enhancing cancer treatment efficacy and offers hope for tackling resistant cancer types.New technology using CRISPR to enhance the immune system’s ability to detect cancer cells has been created, potentially paving the way for innovative cancer treatment methods.Major…

New research demonstrates a significant increase in immune response, up to four times, when alternating arms for multi-dose vaccinations, such as the COVID-19 vaccine. This finding, which emerged from a study involving 947 participants and published in The Journal of Clinical Investigation, challenges previous assumptions that arm choice does not affect immunization effectiveness, with implications for enhancing vaccine efficacy against variants like omicron.COVID-19 vaccine discovery could shape clinical practices…

Researchers have discovered a new class of antibodies capable of neutralizing various flu virus strains, potentially aiding in the development of more broadly protective flu vaccines. This breakthrough, to be published in PLOS Biology, emphasizes the importance of diversifying flu vaccine production methods and provides new avenues for vaccine design.The findings may assist in creating vaccines that offer wider protection against various flu strains.Researchers led by Holly Simmons from the University of Pittsburgh School…

German researchers have developed a novel immunization technique that simplifies and accelerates the development of vaccines. This method, involving the fusion of antigen proteins to a membrane-bound protein, has shown promising results in targeting diseases like COVID-19 and offers potential in the fight against HIV-1.A team of researchers in Germany has created an innovative system for presenting epitopes in mammalian cells, aimed at immunization research. This method is anticipated to significantly aid scientists in…

An illustration of chimeric antigen receptor (CAR)-T cells attacking a cancer cell.Illustration: ART-ur (Shutterstock)A relatively new cancer treatment known as CAR T cell therapy is perhaps more dangerous than we knew. The Food and Drug Administration found evidence that the treatment can potentially raise the risk of secondary cancers and is telling makers of these products to add a boxed warning detailing the risk to their labeling. However, the FDA still says that the positives of CAR T therapy outweigh the potential…

A groundbreaking study by UC San Diego researchers reveals why Staphylococcus aureus (SA) vaccines fail in clinical trials, highlighting how SA tricks the immune system into producing ineffective antibodies and suggesting a new direction in targeting less dominant antigens for future vaccine development.Research conducted at UC San Diego provides insight into the clinical failure of numerous potential vaccines for widespread human infection and proposes a solution to overcome this issue.Staphylococcus aureus (SA) is a…

Sweat, heavy breathing, warm temperatures and lots of people — the gym is the perfect environment for bacteria to thrive in, which is why wiping equipment down is a normal part of gym etiquette. But does a quick wipe really eliminate all those germs? CBC's Marketplace swabbed equipment at several popular national gym chains to find out which surface harbours the most bacteria. With training and supplies from an accredited laboratory in Mississauga, Ont., Marketplace visited some of the largest for-profit gym chains: three…