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insulin

Eating fewer calories can ward off ageing

In terms of proving grand ecological truths the Biosphere 2 experiments were something of a bust. As an illustration of what can happen when somewhat fringe-y science meets extreme wealth they were fascinating. There were fierce fallings-out on both sides of the glass. In 1994 Ed Bass, an oil dynast who had paid for the facility, threw out the management team and handed the reins to Steve Bannon, later a key adviser to Donald Trump. At the same time, though, there was what some took to be a breakthrough in the…

Insufficient Sleep Raises Insulin Resistance in Women

Research funded by the NIH demonstrates that insufficient sleep heightens insulin resistance in women, especially postmenopausal women, potentially increasing the risk of type 2 diabetes. This emphasizes the critical role of adequate sleep in maintaining women’s health and preventing diabetes.Findings highlight insufficient sleep as a modifiable risk factor for type 2 diabetes.Chronic insufficient sleep can increase insulin resistance in otherwise healthy women, with more marked effects in postmenopausal women, according…

High blood insulin levels linked to pancreatic cancer in new study

A new study has found a link between high blood insulin levels, frequently seen in people with obesity and type 2 diabetes, and pancreatic cancer. The researchers say their findings may lead to new cancer prevention strategies and targeting treatments to slow or prevent the progression of the cancer.Obesity and type 2 diabetes (T2D) are among the risk factors for pancreatic cancer, and pancreatic ductal adenocarcinoma (PDAC) is one of the most prevalent, aggressive, and lethal pancreatic cancers. However, the mechanisms…

Over a Billion People Predicted to Be Living With Diabetes by 2050

Diabetes cases are likely to skyrocket over the next few decades, new research out this week has found. The study estimates that more than a billion people worldwide will be living with the chronic condition by 2050—roughly double the amount of cases seen today. The prevalence of diabetes is expected to be especially high in parts of Africa and the Middle East, but dozens of countries could experience substantial increases.Mental Health Apps Are a Privacy NightmareIn the simplest terms, diabetes is defined ashaving

Cancer drug reboots pancreas cells to produce insulin

Researchers have combined a drug that’s normally used to treat cancer with a naturally derived anti-inflammatory to stimulate pancreatic stem cells to grow into insulin-producing cells. The study’s findings could one day lead to an alternative way of restoring insulin production in people with type 1 diabetes.In type 1 diabetics, the pancreas’ beta cells are damaged or destroyed by the body’s immune system, producing little or no insulin. Much research has been undertaken to develop treatments to regenerate beta cells,…

Plant-based insulin derived from lettuce, can be taken orally

Animal cells share some qualities with plant cells, but one key feature ours lack is a rigid cell wall. While this provides structure for plants, it’s also something scientists are increasingly looking at for use in new materials, cellulose technology and, now, insulin delivery.Led by Henry Daniell from the University of Pennsylvania’s School of Dental Medicine, researchers have created a promising plant-based insulin, containing the three peptides that occur naturally in insulin, which can also be ingested orally.Just as…

Scientists Hacked Human Cells to Make Insulin, And It Reversed Diabetes in Mice : ScienceAlert

Scientists have repurposed human stomach cells into tissues that release insulin in response to rising blood sugar levels in a breakthrough that promises an effective way to manage conditions such as type 1 diabetes.The experiment, led by researchers from Weill Cornell Medicine in the US, revealed transplants of gastric insulin-secreting (GINS) cells reversed diabetes in mice.Pancreatic beta cells normally do the job of releasing the hormone insulin in response to elevated sugar levels in the blood. In people with…

Ozempic Craze Has Spawned a Sketchy Black Market, FDA Warns

The Food and Drug Administration is warning people to stay away from suspect sources of semaglutide, the active ingredient in popular weight loss drugs Wegovy and Ozempic. The agency has received reports of adverse effects from people using semaglutide created by compounding pharmacies. Additionally, some of these pharmacies are producing different forms of semaglutide that haven’t been tested for their safety and effectiveness.Mental Health Apps Are a Privacy NightmareSemaglutide is a synthetic and longer-lasting…

Eli Lilly vows insulin prices won’t rise; Novo Nordisk, Sanofi hedge

Eli Lilly CEO Dave Ricks on Wednesday promised not to raise prices on the company's insulin products again — the only executive to do so before a Senate Health Committee hearing on making the life-saving diabetes drug more affordable.Sen. Bernie Sanders, the committee's chair, asked Ricks and the CEOs of Novo Nordisk and Sanofi to commit to "never increase the price of any insulin drug again." The three companies control over 90% of the global insulin market. Ricks was the only executive who outright agreed to Sanders'…

Drug company CEOs will testify at Senate Health on insulin price

In this photo illustration, an insulin pen manufactured by the Novo Nordisk company is displayed on March 14, 2023 in Miami, Florida.Joe Raedle | Getty Images News | Getty ImagesThe top executives of the three drug companies that control 90% of the global insulin market will testify May 10 before the Senate Health Committee on lowering prices of their diabetes drugs, panel Chairman Sen. Bernie Sanders said Friday.Those companies — Eli Lilly, Novo Nordisk and Sanofi — had announced in March that they will slash prices of…