Ovarian

High-grade serous ovarian cancer is not only common but an aggressive, hard-to-treat type of ovarian cancer. A new study has identified the genes involved in forming a particular type of lymphatic tissue which, if growing in tumors, is associated with a better prognosis. The findings may lead to more effective, targeted treatments in the future.Despite advances in immunotherapy, some cancers, such as high-grade serous ovarian cancer (HGSOC), respond poorly to it. HGSOC is the most common type of ovarian cancer and has the…

By the time someone has symptoms of ovarian cancer, it is usually in an advanced state. Treatment is extraordinarily difficult, and, sadly, most people will die. One in 78 women will develop ovarian cancer, and more than 230,000 women in the U.S. are currently affected. Of these, approximately 80 percent have no family history of ovarian cancer and no indication that they were at risk for developing it. In addition to the lack of early symptoms, late stage diagnosis occurs because there is no effective way to screen for…

Despite treatment, the survival rates for women with ovarian cancer remain poor, and the chance of the cancer returning is high. But there could be hope for women whose cancer has returned following chemotherapy in the form of a promising cancer-fighting drug that is currently undergoing clinical trials in the US.The drug, called upifitamab rilsodotin, is an antibody-drug conjugate, a class of drugs designed as targeted therapy for disease treatment. Upifitamab rilsodotin acts like a Trojan horse, tricking its way into…

Ovarian cancer is the fifth biggest cause of cancer death in women, and part of its frustrating stubbornness to treat and high level of recurrence may be down to some surprisingly cellular cooperation.A new study has shed light on the way chemotherapy-resistant quiescent cells behave during and after treatment and how they directly impact the cancer cells around them.Chemotherapy largely targets rapidly dividing cancer cells, which makes the slow-dividing quiescent cells difficult to treat. Researchers from the University…

Pierce Brosnan has admitted that painting with his hands helped him to handle his late wife’s ovarian cancer.The James Bond star was married to Australian actor Cassandra Harris from 1980 to her death in 1991, aged 43. The pair had one son, Sean, together.In a new interview, Brosnan said that he had long been interested in art, with the pages of his script often covered in “repetitions of symbols, self-portraits. Emblems of some Celtic past”.His first show will open at Seasons LA, a gallery in Los Angeles, next…

There is a lot scientists still don’t know about the female reproductive system. They don’t know enough about how to treat the most common vaginal infection, bacterial vaginosis. They don’t have good solutions for many people suffering from endometriosis, a common and sometimes incredibly painful condition where tissue similar to what grows inside the uterus grows elsewhere in the body. They still have a lot of questions about what menopause does to a body. So a few years ago, Rachel Gross, a science reporter who…

This podcast was produced for the AstraZeneca YOUR Cancer program by Scientific American Custom Media, a division separate from the magazine’s board of editors. Transcript: Megan Hall: Every year, the Cancer Community Awards, sponsored by AstraZeneca, presents an individual or organization with a Catalyst for Care Award. This award celebrates those who are making a patient’s experience as easy as possible during an extraordinarily difficult time. In 2021, the non-profit Unite for HER received the award for its work…