progression

Results of an 18-month trial led by US pharmaceutical producer Eli Lilly have shown its new Alzheimer's drug can delay the progression of the disease by up to 35.1 percent.That means across the trial certain patients had their decline slowed down by 4.4 to 7.5 months.It's expected that the drug, called donanemab, will be approved by the US Food and Drug Administration (FDA). This will make it the third medication available to treat the debilitating condition in the US.However, the trial also showed that there were severe…

Neuroscientists have discovered that intensive exercise can slow the progression of Parkinson’s disease. The research unveils a previously unobserved mechanism, providing a path for the development of new non-pharmacological treatments. The study also highlights the neuroprotective effect of exercise, detailing its impact on neuronal survival, brain plasticity, and motor control.Intensive exercise can slow the progression of Parkinson’s disease by improving brain plasticity and neuronal survival, according to a study from…

A comprehensive study involving 22,000 multiple sclerosis patients identified a genetic variant that accelerates disease progression. This breakthrough, achieved by Yale researchers and the International MS Genetics Consortium, found that patients with two copies of the variant, near the DYSF and ZNF638 genes, experienced faster disease progression. This finding opens new avenues for developing treatments to slow MS progression.In a first-of-its-kind breakthrough, a study involving over 22,000 multiple sclerosis patients,…

By Harvard T.H. Chan School of Public Health July 7, 2023An 18-month study found that people with Amyotrophic Lateral Sclerosis (ALS) who maintained higher levels of omega-3 fatty acids in their blood demonstrated a slower rate of physical functional decline and a reduced risk of premature death in comparison to individuals with lower omega-3 levels. Alpha-linolenic acid (ALA), an omega-3 fatty acid abundant in nuts, seeds, and oils, was particularly influential in this correlation. ALS patients with elevated ALA levels…

Payday 3 will launch with new and revamped special enemy types, a new weapon customization and progression systems, as well as altered difficulty settings and smarter enemy AI.In a dev diary with senior game designers Miodrag Kovačević and Jimmy Karlström, as well as lead gameplay programmer Martin Waern, new details about the game's combat were revealed. Payday 3 will launch with four difficulties: Normal, Hard, Very Hard, and Overkill. You will encounter every kind of enemy on every difficulty, as it…

A clinical trial has found that a low dose of the drug atropine, administered daily as an eye drop, could potentially slow the progression of nearsightedness in children, reducing the risk of serious eye health issues later in life. The promising results of this study could pave the way for treatments that not only correct vision but also halt the advancement of the condition.Clinical trial suggests low-dose atropine is an effective myopia treatment.The results of a new clinical trial suggest that the first drug therapy…

Dementia, a prevalent and distressing neurodegenerative disorder, exerts its grip on countless individuals across the globe. This condition manifests through a progressive decline in cognitive functions, including memory impairment and the inability to carry out routine activities. As the disease advances, individuals grappling with dementia encounter substantial challenges in communication, decision-making, and problem-solving skills.Scientists from the University of Helsinki have successfully demonstrated that a…

Photo of iPSCs-derived Motor neurons derived from an ALS patient. Credit: Morimoto et al/Cell Stem CellAmyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease is a lethal neurological disorder that progressively results in individuals losing muscle control. Currently, there is no cure, and the primary focus of treatments is to alleviate symptoms and offer supportive care. Early clinical trial findings recently published in the journal Cell Stem Cell, demonstrated that the drug ropinirole, typically used…

Following the announcement that Blizzard would no longer be adding Hero Missions to Overwatch 2, the team behind the hit first-person shooter has made a concentrated effort to explain what features are still on the way. In a recent livestream dedicated to discussing the game's future and upcoming season, Invasion, the team elaborated on a number of upcoming features including Story missions and a never-before-seen hero progression system.The team opened the presentation by explaining more about the game's…

Overwatch 2 hasn’t been hitting the same for some When I covered Overwatch 2 at its “release,” I was anxiously waiting for the major PVE element that would eventually come down the pipeline. It sounded absolutely fantastic and would have added a true PVE element to the game, something Overwatch sorely needed for longevity. Sadly, those plans were scrapped, and although the team is still excited about what they’re putting out, it’s not the same. But all that is still a little ways out. For those of you who are still…