prostate

Scientists have used artificial intelligence (AI) to reveal a new form of aggressive prostate cancer which they said could help thousands of lives by revolutionising how the disease is diagnosed and treated in the future.The study, published in the journal Cell Genomics, reveals that prostate cancer, which affects one in eight men in their lifetime, includes two different subtypes termed evotypes. The findings, led by researchers at the University of Oxford, and the University of Manchester, UK, could help provide…

A new study has found that, in mouse models of prostate cancer, a compound extracted from sandalwood oil was effective in slowing the onset and growth of tumors and resulted in cell death. Further research will explore whether the extract can be used to treat prostate cancer in humans.While early detection and treatment have improved outcomes for men with prostate cancer, standard treatments such as radio- and chemotherapy can be less effective against advanced forms of the disease – time, then, to look for alternative…

A new study has found that digital rectal examination alone or in combination with a blood test does not improve prostate cancer detection compared to the blood test alone. The findings suggest that digital exams are less effective than thought and could be omitted from prostate cancer screening in men who don’t have clinical signs and symptoms.The go-to methods for screening and detecting prostate cancer are a digital rectal examination (DRE) and a blood test to measure prostate-specific antigen (PSA) levels. PSA is a…

Researchers have identified the gene responsible for setting off a cellular chain reaction that causes prostate cancer to metastasize to the bone, making it almost impossible to treat. The discovery could have significant implications for treating prostate cancer and other solid tumor types in which the gene is present.Bone metastases are common in all types of advanced cancer, but particularly among patients with prostate and breast cancers. When prostate cancer metastasizes to bone, it’s often a death sentence, as there…

Researchers have identified three new prostate cancer biomarkers that improve the visibility of cancer cells used by pathologists to grade the disease’s severity. The novel technique could assist in determining which patients require urgent treatment and those who don’t, potentially improving treatment outcomes for millions of men.In 2020, more than 1.4 million men were diagnosed with prostate cancer, and an estimated 375,304 died. The survival rates for prostate cancer depend on several factors, including the stage and…

An international research team has discovered a novel weak spot in prostate cancer cells, involving a component of the minor spliceosome that is significantly increased in advanced prostate cancer, driving uncontrolled cell growth. The team found that inhibiting this component led to a significant reduction in prostate cancer growth compared to standard therapies, offering potential for more effective, targeted treatments and potentially applicable to other types of cancer.A previously undiscovered weakness in prostate…

Prostate cancer is a common type of cancer that affects men, and it occurs in the prostate gland which is a part of the male reproductive system. High-risk prostate cancer refers to aggressive and advanced forms of the disease that are more likely to spread to other parts of the body. The treatment of high-risk prostate cancer can be challenging as it often requires a combination of therapies, including surgery, radiation, and hormone therapy.According to a phase 2 study conducted by the Johns Hopkins Kimmel Cancer Center…

A trial conducted at the University Hospital Bonn in Germany has found that using PSMA-PET/CT alongside standard imaging techniques to diagnose prostate cancer might help clinicians make improved decisions about subsequent courses of treatment. The scanning method provides a clearer view of suspected tumors during biopsy and detected significantly more clinically significant prostate cancers. However, the technique is not yet available everywhere as it is expensive, and further investigation is needed to see if the final…

Prostate cancer is the second most common cancer and cause of cancer-related death among American men. Researchers have identified crucial molecular factors that contribute to the development of an extremely aggressive form known as neuroendocrine prostate cancer, which currently lacks effective treatments. This discovery opens up new possibilities for developing therapeutics to combat this aggressive form of the disease.Neuronal Molecule Makes Prostate Cancer More AggressiveResearchers discover a potential therapeutic…

A drug used to extend the lives of people with advanced prostate cancer is in short supply and will be for months, leaving some patients with no treatment option as the manufacturer works to ramp up production.  The Food and Drug Administration said last week the availability of Pluvicto is limited as manufacturer Novartis AG struggles to meet demand. The drugmaker said the shortage stems from manufacturing and delivery issues.  Novartis said it is prioritizing the supply for patients who…