An experimental mRNA vaccine, mRNA-4157/V940, combined with immunotherapy pembrolizumab, decreased the likelihood of melanoma recurrence or death by 44% compared to immunotherapy alone in a phase 2b trial. The personalized vaccine, which took 6-8 weeks to develop for each patient, targeted specific abnormal proteins called neoantigens produced by cancer cells, teaching the immune system to recognize cancer cells as distinct from normal cells.A recent clinical trial reveals that the combination of an experimental mRNA…
Photo by Peter Olexa on UnsplashReadings in computational social scienceThis article comments on three papers associated with computational social science research: (1) Do Cascades Recur? (Cheng et al., 2016); (2) Integrating Text and Image: Determining Multimodal Document Intent in Instagram Posts (Kruk et al., 2019); and (3) Statistical Modeling: The Two Cultures (Breiman, 2001); these papers focus on (1) recurrence in content sharing on social media (here, Facebook); (2) the use of multimodal data (image–caption pairs)…
Chemotherapy is an incredible tool for annihilating cancer cells, but our regular cells end up in the crossfire, which can result in life-altering side effects.Chemotherapy or chemo for short is not always required for successful treatment either, but how to tell if someone requires it can be both an art and a science. Now, a new study provides clinicians with a technique that has already helped some stage II colon cancer patients avoid chemo, with no change to their clinical outcomes.
The technique employed in this…