Tata Institute comes up with a ₹100 drug to prevent cancer recurrence; doctors to start human trials soon

The tablet is priced at ₹100 per piece, according to Business Standard.

Also Read | IIT-Madras researchers patent use of Indian spices to treat cancer, medicines likely to be available by 2028

“We did a little experiment in which we took human breast cancer cells and implanted them in immunodeficient mice,” said Dr Indraneel Mittra, the onco-surgeon-turned-scientist who led the TMH doctors in the study, as quoted by Hindustan Times. “Within six weeks, a small tumour was formed. We divided the mice into three categories according to the cancer treatment—chemotherapy, radiotherapy and surgery. We found that all the three treatments increased chromatin in the mouse brain.”

Also Read | Prince Harry ‘outraged’ Queen Camilla, was ‘asked to leave’ on his visit to cancer-stricken King Charles

“We found that a combination of resveratrol and copper helped in destroying chromatin. We used the combination to be given orally in our studies and found that it prevented metastasis,” said Dr Mittra, who added that while this was the outcome of the experiment on mice, the team would now do human trials, as per the HT report. Dr Mittra joined TMH in 1982 as the country’s first “surgeon scientist”.

Also Read | These drug companies are going nuclear to fight cancer

Mittra further explained that after confirming the presence of chromatin particles following cancer treatment, the team’s focus shifted towards reducing treatment-related toxicity (side effects) in various human cancers, such as stomach, brain, oral, and blood cancers through clinical trials, as per the Hindustan Times report.

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Published: 28 Feb 2024, 12:16 PM IST

The tablet is priced at ₹100 per piece, according to Business Standard.

Also Read | IIT-Madras researchers patent use of Indian spices to treat cancer, medicines likely to be available by 2028

“We did a little experiment in which we took human breast cancer cells and implanted them in immunodeficient mice,” said Dr Indraneel Mittra, the onco-surgeon-turned-scientist who led the TMH doctors in the study, as quoted by Hindustan Times. “Within six weeks, a small tumour was formed. We divided the mice into three categories according to the cancer treatment—chemotherapy, radiotherapy and surgery. We found that all the three treatments increased chromatin in the mouse brain.”

Also Read | Prince Harry ‘outraged’ Queen Camilla, was ‘asked to leave’ on his visit to cancer-stricken King Charles

“We found that a combination of resveratrol and copper helped in destroying chromatin. We used the combination to be given orally in our studies and found that it prevented metastasis,” said Dr Mittra, who added that while this was the outcome of the experiment on mice, the team would now do human trials, as per the HT report. Dr Mittra joined TMH in 1982 as the country’s first “surgeon scientist”.

Also Read | These drug companies are going nuclear to fight cancer

Mittra further explained that after confirming the presence of chromatin particles following cancer treatment, the team’s focus shifted towards reducing treatment-related toxicity (side effects) in various human cancers, such as stomach, brain, oral, and blood cancers through clinical trials, as per the Hindustan Times report.

Milestone Alert!
Livemint tops charts as the fastest growing news website in the world 🌏 Click here to know more.

Unlock a world of Benefits! From insightful newsletters to real-time stock tracking, breaking news and a personalized newsfeed – it’s all here, just a click away! Login Now!

Published: 28 Feb 2024, 12:16 PM IST