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2023 was a big year for CRISPR-based gene editing but challenges remain

2023 was an important year for patients with sickle cell disease. Prior to CRISPR, the only cure for the life-long ailment was a bone marrow transplant, which is notoriously dangerous and costly. This month, the FDA approved Vertex’s “Casgevy,” a CRISPR-based therapy for the treatment of sickle cell disease in patients 12 and older. The landmark approval made the therapeutic the first genetically edited therapy to reach the general market.Casgevy, which also received the greenlight from regulators in the UK for another…

Volvo CEO says what lack of EV demand? Orders remain strong

A lack of demand for EVs? Not so fast. Volvo CEO Jim Rowan says new electric models will continue fueling sales. Orders for Volvo EVs like the C40 and EX30 are strong. Volvo was one of the first automakers to commit to going all-electric by 2030. “There is no long-term future for cars with an internal combustion engine,” explained Henrick Green, Volvo CTO in 2021. The early commitment is paying off. Despite rising interest rates and higher inflation, Volvo expects “strong double-digit” sales…

Galaxy S24 lineup prices remain unchanged, satellite feature confirmed

According to the latest report from a Korean news outlet, Samsung is planning to sell its Galaxy S24 trio at the same prices as its predecessors, the Galaxy S23 lineup. Additionally, a separate report seemingly confirms the emergency satellite texting feature for the S24 series. We've heard rumors about the latter quite a few times now, but this leaked screenshot will likely clear all doubts. It clearly states that the unnamed Galaxy S24 phone supports emergency texting via satellite connection, just like the latest…

Destiny 2’s The Final Shape Expansion Could Be Bungie’s Last Chance To Remain Independent, Report Suggests

Behind the scenes at Destiny 2 developer Bungie, morale is reportedly all-time low following mass layoffs at the company and other cost-cutting measures. In a new IGN report, sources at the studio claim that a "soul-crushing" atmosphere has set in and that the company is at risk of being fully absorbed by Sony.While Bungie was acquired by Sony for $3.6 billion in 2022, on paper, the company has still been able to operate relatively independently. In the aftermath of the acquisition, its board of directors…

Altman is back at OpenAI, but questions remain as to why he was fired in first place

Sam Altman is returning to lead OpenAI less than five days after his surprise dismissal, which kicked off a tug of war for his talent, left the company in disarray and laid bare deep board divisions over the mission of one of the world's most valuable startups.OpenAI's new interim board, which won't include Altman at the outset, will be led by Bret Taylor, a former co-CEO of Salesforce Inc. The other directors are Larry Summers, the former US treasury secretary, and existing member Adam D'Angelo, the co-founder and CEO…

“Satya and my top priority remain to ensure OpenAI continues to thrive,” says Sam Altman

On teaming up with Microsoft, recently ousted OpenAI CEO Sam Altman has said that the top priority for Satya Nadella and him would remain to ensure that Open AI continues to thrive. He said that the OpenAI and Microsoft partnership will make this very doable.In a post on social media platform X (formerly Twitter), Sam Altman wrote, "Satya and my top priority remains to ensure OpenAI continues to thrive. We are committed to fully providing continuity of operations to our partners and customers." "The OpenAI/Microsoft…

Mumbai-Pune Expressway To Remain Closed For 6 Hours Today, Here’s Why

Last Updated: November 09, 2023, 11:32 ISTMumbai-Pune Expressway To Remain Closed For 6 Hours Today. (Photo: PTI file)Light & heavy vehicles won't be allowed on the Mumbai-bound carriageway at Chikhale near Kalamboli where a Rail Over Bridge (ROB) is being constructed.The Mumbai Channel on the Mumbai Pune Expressway will be temporarily closed, according to a notification issued by the Mumbai Railway Development Corporation Ltd. (MRDCL).This closure is considered necessary to enable the construction of Panvel-Karjat…

Chinese Smartphone market may remain weak through 2023, IDC says

Chinese smartphone shipments fell 2.1% in the second quarter, extending a market decline that may persist throughout 2023, research house IDC said. The decline came despite widespread discounting during the “6.18” online shopping festival in June. Apple Inc. was one of the few brands that managed to grow business, by 6.1%, IDC estimated in its latest market report. Shipments from Honor Device Co. and Xiaomi Corp. both declined by more than 17% in the quarter, while Huawei Technologies Co. lifted shipments 76.1%, mainly…