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Rogue protein linked to early-onset dementia identified

Scientists have identified odd clusters of a specific protein in the brains of people with early-onset dementia, pointing to a potential cause, a diagnostic tool and, ultimately, a therapy target for a disease that’s been largely a mystery to researchers.Scientists out of the molecular biology lab of the UK’s Medical Research Council (MRC) have pinpointed unusual aggregations of the TAF15 protein in the progression of frontotemporal dementia.While a large body of research is under way to target protein aggregation and…

The best homeworlds in Warhammer 40,000: Rogue Trader

Tactics games have a reputation for being complex, so when you combine that with the massive Warhammer universe, even making your character becomes a challenge. Designing the look of your character in Warhammer 40,000: Rogue Trader is simple enough, but deciding which homeworld you hail from is more than just a background element for your character. Due to the different cultures and environments of each planet, whichever you pick will determine multiple aspects of your character, including Stats and Talents. This…

The best Archetypes in Warhammer 40,000: Rogue Trader

There are few universes as brutal and unforgiving as Warhammer 40,000. Between the demonic forces, the Imperial army, and space itself, your character in Warhammer 40,000: Rogue Trader is up against tough odds. Before you begin your adventure through the Koronus Expanse and pick up allies, you need to design your own character. You could pick one of the premade options, but where’s the fun in that? Among the cosmetic options available, arguably the most important aspect you need to decide is your Archetype. This will…

Could A Rogue Star Save Us From Our Own Extinction? : ScienceAlert

In around a billion years, the sun will become hot enough to boil all the oceans on our planet, and life as we know it will be destroyed.The fate of life on Earth, scientists think, is more or less sealed.But a passing star could prove to be an unlikely savior, according to a new study by scientists from the University of Bordeaux, France, and the Planetary Science Institute in Tucson, Arizona.The researchers ran 12,000 simulations to see what would happen if a star passed within 100 astronomical units (about 9.3 billion…

Review Roundup For Warhammer 40,000: Rogue Trader

Warhammer 40,000: Rogue Trader arrives this week, and the first reviews are starting to come in. As a game that can easily take over 100 hours to finish, many reviews are still in progress, though most critics praised how faithfully Owlcat Games captured the atmosphere of the 40K universe.As an extensive CRPG based on a popular tabletop game, it's inevitable that Rogue Trader has been compared to Baldur's Gate 3 in almost every review, though not always favourably. Reviewers have said that Rogue Trader is…

New Study Lists The Ways a Rogue Star Could Spell Doom For Our Solar System : ScienceAlert

Stars are gravitationally fastened to their galaxies and move in concert with their surroundings. But sometimes, something breaks the bond. If a star gets too close to a supermassive black hole, for example, the black hole can expel it out into space as a rogue star.What would happen to Earth if one of these stellar interlopers got too close?It's not a very likely occurrence, but the chance is not zero.After several billion years, our Solar System has evolved into sedentary predictability. The planets move as they move,…

X-Men Blue Origins’ Big Nightcrawler/Mystique Retcon, Explained

Kurt Wagner’s relationship with Mystique and Destiny has long been a messy, divisive one–but as the current era of X-Men comics is more explicit about their queer family, this week it righted the wrongs of the past to bring Kurt and his upbringing into a bold new light.“Even AI Rappers are Harassed by Police” | AI UnlockedA lot’s happening with the X-Men right now, and mutantkind in general, as Marvel Comics heralds the final months of the “Krakoan Age”—the ascendant period of comics ushered in back in 2019 under the…

Disney Marvel Studios Gift Guide: Loki, Spider-Man, Avengers

Image: MarvelThe whole family can channel their favorite Marvel characters with gifts inspired by the heroes and villains of the MCU, Spider-Man films, Disney+ shows like Loki and Ms. Marvel, and ‘90s X-Men cartoon throwbacks. This holiday season, be merry and Marvel with collections available online and in select stores from retailers like BoxLunch, RSVLTS, Loungefly, Chewy, and Heroes & Villains. From accessories to baby outfits to pet gifts—io9 has you covered in this and every timeline.Check out our Marvel style

AI predicts when and where “monster” rogue waves will swell up

Gigantic waves can seemingly come out of nowhere, threatening ships and oil rigs. Now, an AI system trained on centuries of data has been able to predict when these rogue waves will occur, revealing new insights into how they form.Rogue waves don’t necessarily have to be the biggest waves in the ocean – by definition they just need to stand at least twice as high as surrounding waves. They form due to interactions between things like currents and winds, which separates them from larger, more destructive waves like…