Cancers

New research reveals that stress promotes cancer metastasis by causing neutrophils to form structures that facilitate the disease’s spread. This finding highlights the importance of incorporating stress reduction into cancer treatment and suggests new avenues for preventing cancer metastasis through targeted therapies.Stress is an unavoidable aspect of life. However, excessive stress can have detrimental effects on our health. Prolonged stress elevates the risk of developing heart disease and experiencing strokes. It may…

A groundbreaking study by UC San Francisco and Northwestern Medicine showcases a new T-cell therapy that significantly enhances the ability of engineered T cells to fight solid tumors, offering a potential new pathway for cancer treatment. Credit: SciTechDaily.comBy leveraging mutations from cancerous cells, researchers have engineered T cells that are over 100 times more potent against cancer, promising a new era in immunotherapy for solid tumors.Immunotherapies using engineered T cells have ushered in a new era in…

Researchers at UC Riverside have made a groundbreaking discovery in cancer treatment by developing a peptide that can control MYC, a key protein involved in the majority of human cancers. This innovation offers new hope for targeting cancer at a molecular level, paving the way for more effective treatments.Discovery paves the way for more effective treatment.Meet MYC, the shapeless protein responsible for making the majority of human cancer cases worse. UC Riverside researchers have found a way to rein it in, offering…

ReSisTrace is a groundbreaking method that tracks cancer cell resistance by using genetic barcodes, revealing how some cells evade treatment. This insight guides the development of drugs that can turn resistant cells back to a state where they can be effectively targeted by existing therapies. Credit: SciTechDaily.comBy genetically labeling cancer cells, ReSisTrace uncovers pre-existing resistant states, leading to targeted therapies that prevent treatment evasion, offering a new frontier in personalized cancer care.In…

Acute myeloid leukemia (AML) isn’t the most commonly known cancer. It is, however, one of the deadliest—an awful rare malignancy of the blood and bone marrow whose victims are already older and frail, on average 68 years old when diagnosed. It has few treatment options—chemotherapy is most common, according to the American Cancer Society—and any available ones must be deployed immediately after it’s diagnosed given how rapidly this aggressive cancer spreads. Nearly 70% of AML patients die within five years of diagnosis,…

Scientists have identified that the spread of cancer and the formation of deadly metastases are influenced by DNA methylation patterns and the role of endothelial cells, offering new insights into cancer treatment and patient prognosis. Credit: SciTechDaily.comResearch highlights the critical role of endothelial cells and DNA methylation in cancer metastasis, pointing to new strategies for diagnosis and therapy.Scientists from the German Cancer Research Center (DKFZ) and Heidelberg University investigated in mice how…

The protein MYC is part of healthy cell activity, but when cancer cells develop, it goes haywire – going outside of its normal, carefully controlled role and helping cancer to spread. Now, scientists may have found a way to stop this from happening.Part of the problem in reining in MYC is that it's a shapeless protein, one that doesn't really have a structure that can be targeted. That makes it difficult for drugs to effectively identify MYC and keep it behaving normally.However, a team from the University of California,…

The FDA has granted clearance for the first AI-powered handheld medical device to assist physicians in detecting all three common skin cancers: basal cell carcinoma, squamous cell carcinoma, and melanoma. Providing a more accurate way of identifying skin cancer will enable patients to access necessary treatment more quickly.According to current estimates, one in five Americans will develop skin cancer in their lifetime. The three most common skin cancers are basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and…

An illustration of chimeric antigen receptor (CAR)-T cells attacking a cancer cell.Illustration: ART-ur (Shutterstock)A relatively new cancer treatment known as CAR T cell therapy is perhaps more dangerous than we knew. The Food and Drug Administration found evidence that the treatment can potentially raise the risk of secondary cancers and is telling makers of these products to add a boxed warning detailing the risk to their labeling. However, the FDA still says that the positives of CAR T therapy outweigh the potential…

Researchers have uncovered a significant link between inherited genetic variants and the development of a rare blood cancer, myeloproliferative neoplasms (MPN). This breakthrough could improve clinical predictions and inform future treatments. Credit: SciTechDaily.comA groundbreaking study reveals how inherited genetic variants contribute to the development of rare blood cancer, offering insights for disease prediction and treatment strategies.Large-scale genetic analysis has helped researchers uncover the interplay…