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Daily tablet slows diabetes progression in clinical trial

A world-first clinical trial has found that baricitinib, a drug commonly prescribed for rheumatoid arthritis, preserved the pancreatic cells’ ability to produce their own insulin and slowed the progression of type 1 diabetes in those recently diagnosed with the condition. The drug shows promise as the first disease-modifying treatment for type 1 diabetes that can be given as a tablet.Type 1 diabetes occurs when the body’s immune system attacks and destroys the pancreas’ insulin-secreting cells. However, because the…

Stem cell injections help slow progression of MS in clinical trial

Multiple sclerosis (MS) is a debilitating disease with few treatment options. But in a new clinical trial, scientists have tested a promising new therapy involving injections of stem cells, which seems to slow progression of the disease.In patients with MS, the immune system begins mistakenly attacking myelin, the tissue that encases and protects nerve fibers. As this sheath sustains more and more damage, it disrupts electrical signals traveling through nerves, resulting in reduced mobility, balance, sensation and muscle…

Many people aren’t represented in anatomy drawings. These professors are changing that

Crack open just about any textbook dealing with medicine or science, and you'll see a lot of the same when it comes to the human anatomy illustrations: often white male bodies, usually very physically fit, absent tattoos, piercings or prosthetics. A duo of professors working in kinesiology and anatomy — including one from the University of Windsor — is hoping to change that by creating a new series of anatomy images. "The standard images that you see in textbooks don't really show the racial diversity that … I see, when I…

Pregnant people, children face ‘dire’ health consequences from climate change, WHO warns

This story is part of CBC Health's Second Opinion, a weekly analysis of health and medical science news emailed to subscribers on Saturday mornings. If you haven't subscribed yet, you can do that by clicking here.The impacts of climate change hit Canada hard in recent years, from the deadly heat dome of 2021 to the country's worst-ever wildfire season last summer. And those devastating environmental disasters provoked a lot of anxiety among pregnant individuals."Pregnancy, even without heat and smoke, is a time when…

Drug that makes humans regrow lost teeth will soon enter clinical trials

Some animals, like crocodiles and geckos, can regrow their teeth, replacing them throughout their lifetime. However, the ability to endlessly replace lost teeth has been beyond human reach for quite a while. Now, though, a team of scientists may have created a tooth-growing drug that lets us regrow teeth that we’ve lost, and it’s set to enter a promising clinical trial very soon. Tech. Entertainment. Science. Your inbox. Sign up for the most interesting tech & entertainment news out there. By signing…

This drug developed by AI for lungs disease enters human clinical trials

The use case scenario of artificial intelligence is growing faster than expected. AI is being used in several key industries to make things more efficient and effective. The latest industry to become onboard on AI-based systems is the pharma industry and recently a drug for curing liver disease known as Idiopathic Pulmonary Fibrosis (IPF), a disease that causes scarring in the lungs, has been discovered and designed using artificial intelligence has entered into human clinical trials. Clinical trial for INS018_55 has…

NIH toughens enforcement of delayed clinical trials reporting | Science

Last year, the U.S. National Institutes of Health (NIH) delivered a stern warning to two in-house clinical researchers who had broken an important rule. They had failed to submit the results of two clinical trials they had overseen to ClinicalTrials.gov, a database meant to inform the public about human studies and their results. The reporting requirement has often been ignored, but this time the agency took an unprecedented step: It told the scientists it…

Elon Musk’s Neuralink reports FDA approval of an in-human clinical study

Elon Musk’s brain-computer interface company Neuralink says it has received Food and Drug Administration (FDA) approval to launch its first in-human clinical study. If this is true, it means that actual humans could be getting a device from Neuralink implanted in their heads.The news follows Elon Musk’s November claim that Neuralink was about six months away from its first human trial — which suggests it’s the rare Musk promise that’s actually coming true on time. The announcement of a future human trial isn’t nearly as…

New Weight Loss Drug May Launch in US After Promising Clinical Trial : ScienceAlert

Pharmaceutical giant Eli Lilly said Thursday it will seek approval to add its diabetes drug to the buzzy US weight loss market after achieving promising results in a new clinical trial.Tirzepatide, currently approved to treat type 2 diabetes under the name Mounjaro, is taken once a week as an injection.Eli Lilly said its trial was conducted over a period of 72 weeks on just over 900 overweight or obese participants with type 2 diabetes.Those who received the highest dosage lost an average of 15.7 percent of their body…